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Intensity of Oxidative Stress in Mongoloid and Caucasian Patients with Type 1 Diabetes Mellitus

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Specific features of LPO were studied in Mongoloid and Caucasian patients with type 1 diabetes mellitus. The intensity of LPO in Mongoloid patients was lower than in Caucasians: the level of primary and intermediate products was by lower 1.53 and 1.83 times, while total antioxidant activity was elevated by 1.44 times, which was also supported by oxidative stress coefficient (1.35 in Mongoloids and 2.32 in Caucasians). These differences suggest that differentiated approach is required for the treatment of these patients.

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References

  1. Volchegorskii IA, Nalimov AG, Yarovinskii BG, Lifshits RI. A comparison of different approaches to measurements of LPO products in heptane-isopropanol extracts of the blood. Vopr. Med. Khimii. 1989;35(1):127-131. Russian.

  2. Gavrilov VB, Gavrilova AR, Mazhul’ LM. Analysis of methods for measurements of LPO products in the blood serum by the test with thiobarbituric acid. Vopr. Med. Khimii. 1987;33(1):118-121. Russian.

  3. Dedov II, Kolesnikova LI, Ivanova ON, Bardymova TP, Karlova NG, Atamanova TM, Prokof’ev SA. Gene polymorphism in HLA class II and CTLA4 genes in healthy Buryats and patients with type 1 diabetes in the Buryat Republic. Sakh. Diabet. 2006;(1):2-8. Russian.

  4. Klebanov GI, Babenkova IV, Teselkin YuO, Komarov OS, Vladimirov YuA. Evaluation of antioxidant activity of blood plasma using yolk lipoprotein. Lab. Delo. 1988;(5):59-62. Russian.

  5. Kolesnikova LI, Darenskaya MA, Grebenkina LA, Suturina LV, Labygina AV, Semenova NV, Tsyrenov TB, Darzhaev ZYu, Kurashova NA, Tolpygina OA. State features of the antioxidant system at healthy people of the basic ethnic groups of Baikal Lake. Vopr. Pitaniya. 2012;81(3):46-51. Russian.

  6. Kolesnikova LI, Kurashova NA, Grebenkina LA, Dolgikh MI, Labygina AV, Suturina LV, Dashiev BG, Darzhoev ZYu. Peculiarities of oxidative stress in men of different ethnic groups with obesity and infertility. Zdorov’e. Med. Ekol. Nauka. 2011;44(1):38-41. Russian.

  7. Kolesnikova LI, Semyonova NV, Grebenkina LA, Darenskaya MA, Suturina LV, Gnusina SV. Integral indicator of oxidative stress in human blood. Bull. Exp. Biol. Med. 2014;157(6):715-717.

    Article  CAS  PubMed  Google Scholar 

  8. Kolesnikova LI, Suturina LV, Labigina AV, Leshenko OYa, Fiodorov BA, Sholokhov LF, Safronenko AV, Lebedeva LN, Lazareva LM, Nadelyaeva YaG. Abnormalities of reproductive health and reproductive potential in present-day conditions of Eastern Siberia. Byull. Vostoch.-Sib. Nauch. Tsentra Sib. Otdel. Ross. Akad. Med. Nauk. 2007;(2):41-43. Russian.

  9. Nelaeva AA, Konoplin RB, Konoplina EV. Genetic markers of type I diabetes mellitus in the Khanty population. Med. Nauka Obrazovanie Urala. 2007;8(5):50-51. Russian.

  10. Suntsov YuI, Dedov II, Maslova OV, Bolotoskaya LL, Shishkina NS, Andianova EA, Maksimiva VP, Prokof’ev SA. The risk of type 1 diabetes in the population of Bashkirs (according to HLA-genotyping data). Sakh. Diabert. 2006;(2):2-6. Russian.

  11. Cheryauskene RCh, Varshkyavichene ZZ, Gribauskas PS. Parallel measurements of the concentrations of vitamins E and A in the serum. Lab. Delo. 1984;(6):362-365. Russian.

  12. Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 1976;74(1):214-226.

    Article  CAS  PubMed  Google Scholar 

  13. Kolesnikova LI, Madaeva IM, Semenova NV, Vlasov BY, Grebenkina LA, Darenskaya MA, Dolgikh MI. Antioxidant potential of the blood in men with obstructive sleep breathing disorders. Bull. Exp. Biol. Med. 2013;154(6):731-733.

    Article  CAS  PubMed  Google Scholar 

  14. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 1972;247(10):3170-3175.

    CAS  PubMed  Google Scholar 

  15. Stadler K. Oxidative stress in diabetes. Adv. Exp. Med. Biol. 2012;771:272-287.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Research Center of Family Health Problems and Human Reproduction, Irkutsk, Russia

    L. I. Kolesnikova, B. Ya. Vlasov, S. I. Kolesnikov, M. A. Darenskaya, L. A. Grebenkina, N. V. Semenova & O. A. Vanteeva

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  1. L. I. Kolesnikova
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  2. B. Ya. Vlasov
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  3. S. I. Kolesnikov
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  4. M. A. Darenskaya
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  5. L. A. Grebenkina
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  6. N. V. Semenova
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  7. O. A. Vanteeva
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Corresponding author

Correspondence to M. A. Darenskaya.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 6, pp. 719-722, June, 2016

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Kolesnikova, L.I., Vlasov, B.Y., Kolesnikov, S.I. et al. Intensity of Oxidative Stress in Mongoloid and Caucasian Patients with Type 1 Diabetes Mellitus. Bull Exp Biol Med 161, 767–769 (2016). https://doi.org/10.1007/s10517-016-3505-0

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  • DOI: https://doi.org/10.1007/s10517-016-3505-0

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