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Effect of Selenium-Containing Products on Antioxidant Enzyme Activity in the Kidneys, Liver, and Blood of Guinea Pigs

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The antioxidant system of some tissues in guinea pigs with no selenium deficiency was studied after treatment with selenium-containing products. Activity of a selenium-containing enzyme glutathione peroxidase was significantly reduced in the kidneys and blood. The kidneys were characterized by low activity of glutathione reductase and high activity of SOD. These features illustrate the development of oxidative stress in the kidneys.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia

    T. V. Sirota

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  1. T. V. Sirota
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Correspondence to T. V. Sirota.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 4, pp. 396–399, April, 2010

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Sirota, T.V. Effect of Selenium-Containing Products on Antioxidant Enzyme Activity in the Kidneys, Liver, and Blood of Guinea Pigs. Bull Exp Biol Med 149, 412–415 (2010). https://doi.org/10.1007/s10517-010-0958-4

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  • DOI: https://doi.org/10.1007/s10517-010-0958-4

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