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Relationship between the Degree of Cardiovascular Adaptation and Th1/Th2 Polarization of Immune Response

  • Sports Medicine
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

The main parameters of humoral immunity during medium intensity exercise were studied in oarsmen with high and low cardiovascular adaptation. A relationship between high cardiovascular adaptation to exercise and immune response polarization by the Th2 mechanism was demonstrated. Increased production of IL-10 in response to physical stress plays a key role in this relationship.

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Authors and Affiliations

  1. DNA-Technology Company, Moscow, Russia

    A. E. Donnikov

  2. National Institute of Physical Culture and Sports, Moscow, Russia

    M. U. Shkurnikov, E. B. Akimov & A. G. Tonevitsky

Authors
  1. A. E. Donnikov
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  2. M. U. Shkurnikov
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  3. E. B. Akimov
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  4. A. G. Tonevitsky
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Corresponding author

Correspondence to A. E. Donnikov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 146, No. 10, pp. 442–445, October, 2008

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Donnikov, A.E., Shkurnikov, M.U., Akimov, E.B. et al. Relationship between the Degree of Cardiovascular Adaptation and Th1/Th2 Polarization of Immune Response. Bull Exp Biol Med 146, 462–465 (2008). https://doi.org/10.1007/s10517-009-0334-4

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  • DOI: https://doi.org/10.1007/s10517-009-0334-4

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