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Exercise Regulates the Immune System

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Physical Exercise for Human Health

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1228))

Abstract

The profound effect of exercise on the normal functioning of the immune system has been well-known. Exercise and immune regulation are interrelated and affect each other. Exercise changes immune regulation by affecting leucocytes, red blood cells, and cytokines, etc. Regular exercise could reduce the risk of chronic metabolic and cardiorespiratory diseases, partially by the anti-inflammatory effects of exercise. However, these effects are also likely to be responsible for the suppressed immunity that make our bodies more susceptible to infections. Here we summarize the known mechanisms by which exercise—both acute and chronic—exerts its immune regulation effects.

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Acknowledgments

This work was supported by the grants from National Natural Science Foundation of China (81722008, 91639101, and 81570362 to JJ Xiao), Innovation Program of Shanghai Municipal Education Commission (2017-01-07-00-09-E00042 to JJ Xiao), the grant from Science and Technology Commission of Shanghai Municipality (17010500100, 18410722200 to JJ Xiao), the development fund for Shanghai talents (to JJ Xiao), and the Sailing Program from Science and Technology Commission of Shanghai (19YF1415400 to J Wang).

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  1. Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, School of Life Science, Shanghai University, Shanghai, China

    Jing Wang, Shuqin Liu & Junjie Xiao

  2. Cardiovascular Division of the Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    Guoping Li

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  1. Jing Wang
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  2. Shuqin Liu
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  3. Guoping Li
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  4. Junjie Xiao
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Correspondence to Junjie Xiao .

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  1. Cardiac Regeneration and Ageing Lab Institute of Cardiovascular Sciences School of Life Science, Shanghai University, Shanghai, China

    Junjie Xiao

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Wang, J., Liu, S., Li, G., Xiao, J. (2020). Exercise Regulates the Immune System. In: Xiao, J. (eds) Physical Exercise for Human Health. Advances in Experimental Medicine and Biology, vol 1228. Springer, Singapore. https://doi.org/10.1007/978-981-15-1792-1_27

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