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Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The concentration of high-density lipoprotein cholesterol and triglycerides in rat serum sharply decreased after psychic trauma caused by life hazard. The content of these substances remained unchanged for not less than 1 week after trauma. The concentration of high-density lipoprotein cholesterol was low, while serum content of triglycerides increased 6 weeks after trauma. The concentration of high-density lipoprotein cholesterol significantly decreased after repeated psychic trauma. These changes were accompanied by a sharp increase in the concentration of triglycerides in the serum. Total cholesterol concentration in the liver decreased under these conditions.

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Authors and Affiliations

  1. I. P. Pavlov Department of Physiology, Department of Biochemistry, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg

    S. G. Tsikunov, N. N. Klyueva, A. G. Kusov, T. V. Vinogradova, V. M. Klimenko & A. D. Denisenko

Authors
  1. S. G. Tsikunov
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  2. N. N. Klyueva
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  3. A. G. Kusov
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  4. T. V. Vinogradova
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  5. V. M. Klimenko
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  6. A. D. Denisenko
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Corresponding author

Correspondence to S. G. Tsikunov.

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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 141, No. 5, pp. 575–578, May, 2006

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Tsikunov, S.G., Klyueva, N.N., Kusov, A.G. et al. Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma. Bull Exp Biol Med 141, 636–638 (2006). https://doi.org/10.1007/s10517-006-0240-y

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  • DOI: https://doi.org/10.1007/s10517-006-0240-y

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