Abstract
We studied the effects of taurine, carnosine, and casomorphine on histamine release from rat peritoneal mast cells induced by compound 48/80 and ionophore A23187. Differences were revealed in the effect of the test preparations. Taurine inhibited histamine release induced by ionophore A23187, but not by compound 48/80. Carnosine abolished the stimulatory effect of compound 48/80 on histamine release, but did not modulate the effect of ionophore A23187. Casomorphine inhibited histamine release induced by ionophore A23187, but potentiated the effect of compound 48/80. The mechanisms for these effects are discussed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. A. Boldyrev, Carnosine [in Russian], Moscow (1998).
E. E. Graevskaya and E. N. Goncharenko, Biol. Nauki, No. 2, 5–14 (1980).
I. S. Gushchin, Immediate Cell Allergy [in Russian], Moscow (1976).
V. A. Kostyuk, A. I. Potapovich, and Zh. V. Kovaleva, Vopr. Med. Khim., No. 2, 88–90 (1990).
I. G. Mikheeva, O. B. Kurasova, T. G. Vereshchagina, et al., Vopr. Detskoi Dietol., 2, No. 4, 21–25 (2004).
J. A. Blunk, M. Schmelz, S. Zeck, et al., Anesth. Analg., 98, No. 2, 364–370 (2004).
P. Bradding, Chem. Immunol. Allergy, 87, 163–178 (2005).
X. Ferry, S. Brehin, R. Kamel, and Y. Landry, Peptides, 23, No. 8, 1507–1515 (2002).
H. Gurer, H. Ozgunes, E. Saugin, and N. Ercal, Arch. Environ. Contam. Toxicol., 41, No. 4, 397–402 (2001).
H. Meisel, Biopolymers, 43, No. 2, 119–128 (1997).
Y. Ohta, T. Kobayashi, K. Inui, et al., Eur. J. Pharmacol., 487, Nos. 1–3, 223–232 (2004).
S. Piemo, A. De Luka, S. Camerino, et al., J. Pharmacol. Exp. Ther., 286, No. 3, 1183–1190 (1998).
I. L. Thon and B. Uvnas, Acta Physiol. Scand., 71, No. 4, 303–315 (1967).
E. Waters, J. H. Wang, H. P. Redmond, et al., Am. J. Physiol. Gastrointest. Liver Physiol., 280, No. 6, G1274–G1279 (2001).
J. R. White, T. Ishizaka, K. Ishizaka, and R. I. Sha’afi, Proc. Natl. Acad. Sci. USA, 81, 3978–3982 (1984).
Author information
Authors and Affiliations
Corresponding author
Additional information
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 3, pp. 302–305, March, 2006
Rights and permissions
About this article
Cite this article
Akhalaya, M.Y., Baizhumanov, A.A. & Graevskaya, E.E. Effects of taurine, carnosine, and casomorphine on functional activity of rat peritoneal mast cells. Bull Exp Biol Med 141, 328–330 (2006). https://doi.org/10.1007/s10517-006-0162-8
Received:
Issue Date:
DOI: https://doi.org/10.1007/s10517-006-0162-8