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Staging Intra-Abdominal Desmoid Tumors in Familial Adenomatous Polyposis: A Search for a Uniform Approach to a Troubling Disease

  • Original Contribution
  • Published:
Diseases of the Colon & Rectum

INTRODUCTION

Desmoid tumors are a clinical problem in 12 to 15 percent of patients with familial adenomatous polyposis. There is no predictably effective treatment for intra-abdominal desmoid tumors, which sometimes cause significant complications by their effects on the ureters or bowel. The relative rarity and the clinical heterogeneity of intra-abdominal desmoid tumors make randomized studies difficult to do. In this article a staging system is proposed to make multi-institutional studies easier.

METHODS

Intra-abdominal desmoid tumors can be staged according to their size, clinical presentation and growth pattern.

CONCLUSION

A way of staging intra-abdominal desmoid tumors is proposed to facilitate stratification by disease severity during collaborative studies of various treatments.

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Author information

Authors and Affiliations

  1. Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio

    James Church M.B.Ch.B.

  2. Familial Cancer Registry, Mount Sinai Hospital, Toronto, Ontario, Canada

    Terri Berk

  3. Jefferson Hereditary Cancer Center, Philadelphia, Pennsylvania

    Bruce M. Boman M.D., Ph.D.

  4. Sloan Kettering Cancer Center, New York, New York

    Jose Guillem M.D.

  5. St. Vincent Hospital, Fitzroy, Victoria, Australia

    Craig Lynch M.B.Ch.B.

  6. MD Anderson Cancer Center, University of Texas, Houston, Texas

    Patrick Lynch M.D. & Miguel Rodriguez-Bigas M.D.

  7. Department of Colon and Rectal Surgery, Lahey Clinic, Burlington, Massachusetts

    Larry Rusin M.D.

  8. New York Metro Familial Cancer Registry, Albert Einstein College of Medicine, New York, New York

    Tom Weber M.D.

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  1. James Church M.B.Ch.B.
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  2. Terri Berk
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  4. Jose Guillem M.D.
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  5. Craig Lynch M.B.Ch.B.
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Church, J., Berk, T., Boman, B. et al. Staging Intra-Abdominal Desmoid Tumors in Familial Adenomatous Polyposis: A Search for a Uniform Approach to a Troubling Disease. Dis Colon Rectum 48, 1528–1534 (2005). https://doi.org/10.1007/s10350-005-0018-8

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  • DOI: https://doi.org/10.1007/s10350-005-0018-8

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