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New drugs from marine microbes: the tide is turning

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Journal of Industrial Microbiology and Biotechnology

Abstract

This is a mini-review demonstrating that investigation of the genomics of marine microbes from all three domains has the potential to revolutionize the search for secondary metabolites originally thought to be the product of marine invertebrates. The basis for the review was a symposium at the 2005 Annual Meeting of the SIM covering some aspects of the potential for marine microbes to be the primary producers of such metabolites. The work reported at that symposium has been integrated into a fuller discussion of current published literature on the subject with examples drawn from bacteria, cyanophytes and fungi.

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Acknowledgements

Russell T. Hill gratefully acknowledges funding from the Microbial Observatories Program, National Science Foundation (MCB-0238515).

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Authors and Affiliations

  1. Natural Products Branch, Developmental Therapeutics Program, NCI-Frederick, P. O. Box B, Frederick, MD, 21702, USA

    David J. Newman

  2. Center of Marine Biotechnology, University of Maryland Biotechnology Institutes, 701 Pratt Street, Baltimore, MD, 21202, USA

    Russell T. Hill

Authors
  1. David J. Newman
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  2. Russell T. Hill
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Corresponding author

Correspondence to David J. Newman.

Additional information

Contribution No. 05-140 from the Center of Marine Biotechnology.

D.J. Newman and R.T. Hill contributed equally.

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Newman, D.J., Hill, R.T. New drugs from marine microbes: the tide is turning. J IND MICROBIOL BIOTECHNOL 33, 539–544 (2006). https://doi.org/10.1007/s10295-006-0115-2

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  • DOI: https://doi.org/10.1007/s10295-006-0115-2

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