Abstract
Treatment of postprandial hypotension (PPH) is often unsuccessful. We report a case of a type 1 diabetic patient suffering from severely symptomatic PPH. The patient was treated with acarbose and showed definite improvement of both glycemic control and PPH.
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References
Aronow WS, Ahn C (1997) Association of postprandial hypotension with incidence of falls, syncope, coronary events, stroke, and total mortality at 29-month follow-up in 499 older nursing home residents. J Am Geriatr Soc 45:1051–1053
Burger AJ, Weinrauch LA, D’Elia JA, et al. (1999) Effects of glycemic control on heart rate variability in type I diabetic patients with cardiac autonomic neuropathy. Am J Cardiol 84:687–691
Campbell IW, Ewing DJ (1976) Therapeutic experience with fludrocortisone in diabetic postural hypotension. Br Med J 1:872–874
Hoeldtke RD, Israel BC (1989) Treatment of orthostatic hypotension with octreotide. J Clin Endocrinol Metab 68:1051–1059
Kohara K, Jiang Y, Igase M, Takata Y, Fukuota T, Okara T, Kitami Y, Hiwada K (1999) Postprandial hypotension is associated with asymptomatic cerebrovascular damage in essential hypertensive patients. Hypertension 33:565–568
Marfella R, Nappo F, De Angelis L, Paolisso G, Tagliamonte MR, Giugliano D (2000) Hemodynamic effects of acute hyperglycemia in type 2 diabetic patients. Diabetes Care 23:658–663
Mathias CJ (1991) Postprandial hypotension. Pathophysiological mechanisms and clinical implications in different disorders. Hypertension 18:694–704
Purewal TS, Watkins PJ (1995) Postural hypotension in diabetic autonomic neuropathy: a review. Diabet Med 12:192–200
Ranganath L, Norris F, Morgan L, Wright J, Marks V (1998) Delayed gastric emptying occurs after acarbose administration and is a further mechanism for its anti-hyperglycaemic effect. Diabet Med 15:120–124
Russo A, Stevend JE, Wilson T, Wells F, Tonkin A, Horowitz M, Jones KL (2003) Guar attenuates fall in postprandial blood pressure and slows gastric emptying of oral glucose in type 2 diabetes. Dig Dis Sci 48:1221–1229
Sasaki E, Goda K, Nagata K, Kitaota H, Ohsawa N, Hanafusa T (2001) Acarbose improved severe postprandial hypotension in a patient with diabetes mellitus. J Diabetes Compl 15:158–161
Sasaki E, Kitaoka H, Ohsawa N (1992) Postprandial hypotension in patients with non-insulin-dependent diabetes mellitus. Diab Res Clin Pract 18:113–121
The Diabetes Control and Complications Trial Research Group (1998) The effect of intensive diabetes therapy on measures of autonomic nervous system function in the Diabetes Control and Complications Trial (DCCT).Diabetologia 41:416–423
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Maule, S., Tredici, M., Dematteis, A. et al. Postprandial hypotension treated with acarbose in a patient with type 1 diabetes mellitus. Clin Auton Res 14, 405–407 (2004). https://doi.org/10.1007/s10286-004-0220-0
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DOI: https://doi.org/10.1007/s10286-004-0220-0