References
Onoue M, Terada T, Kobayashi M et al (2009) UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients. Int J Clin Oncol 14:136–142
Hoskins JM, Goldberg RM, Qu P et al (2007) UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. J Natl Cancer Inst 99:1290–1295
Takano M, Kato M, Yoshikawa T et al (2009) Clinical significance of UDP-glucuronosyltransferase 1A1*6 for toxicities of combination chemotherapy with irinotecan and cisplatin in gynecologic cancers: a prospective multi-institutional study. Oncology 76:315–321
Ichikawa W, Araki K, Fujita K et al (2008) Re: UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. J Natl Cancer Inst 100:224–225
Conflict of interest statement
No author has any conflict of interest.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Takano, M., Kato, M., Yoshikawa, T. et al. Indispensability of UGT1A1*6 genotyping in Japanese cancer patients treated with irinotecan. Int J Clin Oncol 15, 224–225 (2010). https://doi.org/10.1007/s10147-010-0024-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10147-010-0024-2