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Poly(maleic anhydride-co-acrylic acid)/poly(ethylene glycol) hydrogels with pH- and ionic-strength-responses

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Abstract

Poly(maleic anhydride-co-acrylic acid), P(MA-AA), was synthesized by the free-radical copolymerization of maleic anhydride with acrylic acid, and fast responsive pH-sensitive poly(maleic anhydride-co-acrylic acid)/polyethylene glycol, P(MA-AA)/PEG, hydrogels were prepared using PEG as macromolecular cross-linking agent. FT-IR and 1H-NMR spectrometry were applied to characterize the structure of P(MA-AA). The influences of pH and ionic strength on the swelling behavior of P(MA-AA)/PEG hydrogels and the swelling-deswelling changes along with the repeated changes between acid and alkali conditions were studied. The results showed that there was a hundredfold difference in the swelling ratios between the conditions of acid and alkali, and the swelling capability could not be weakened after multiple swelling-deswelling cycles. The results of swelling kinetics demonstrated that the response rate of P(MA-AA)/PEG hydrogels was very fast, because the swelling transition points always occurred at 10 min. The pH-responsive hydrogels reported here might be a smart material for potentially applications in many areas, including biosensors, drug-delivery devices and tissue engineering.

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References

  1. Xiao, X.C., Chu, L.Y., Chen, W.M., Wang, S. and Li, Y., Adv. Funct. Mater., 2003, 13: 847

    Article  CAS  Google Scholar 

  2. Mandracchia, D., Pitarresi, G., Palumbo, F.S., Carlisi, B. and Giammona, G., Biomacromolecules, 2004, 5: 1973

    Article  CAS  Google Scholar 

  3. Komarova, G.A., Starodubtsev, S.G., Lozinsky, V.I., Kalinina, E.V., Landfester, K. and Khokhlov, A.R., Langmuir, 2008, 24: 4467

    Article  CAS  Google Scholar 

  4. Deshmukh, S., Mooney, D.A., McDermott, T., Kulkarni, S. and MacElroy, J.M.D., Soft Matter, 2009, 5: 1514

    Article  CAS  Google Scholar 

  5. Yarimkaya, S. and Basan, H., J. Macromol. Sci., Part A: Pure Appl. Chem., 2007, 44: 939

    Article  CAS  Google Scholar 

  6. Yarimkaya, S. and Basan, H., J. Macromol. Sci., Part A: Pure Appl. Chem., 2007, 44: 699

    Article  CAS  Google Scholar 

  7. Jin, X. and Hsieh, Y.L., Polymer, 2005, 46(14): 5149

    Article  Google Scholar 

  8. Luo, R., Li, H. and Lam, K.Y., Anal. Bioanal. Chem., 2007, 389(3): 863

    Article  CAS  Google Scholar 

  9. Zhang, J. and Peppas, N.A., Macromolecules, 2000, 33(1): 102

    Article  CAS  Google Scholar 

  10. Liu, N., Yi, M., Chen, S.J. and Ha, H.F., Chinese J. Polym. Sci., 2002, 20(5): 409

    CAS  Google Scholar 

  11. Ali, A.E.H. and Hegazy, E.S.A., J. Biomed. Mater. Res. Part B: Appl. Biomater., 2007, 81B: 168

    Article  Google Scholar 

  12. Pfister, P.M., Wendlandt, M., Neuenschwander, P. and Suter, U.W., Biomaterials, 2007, 28: 567

    Article  CAS  Google Scholar 

  13. Ni, H.M., Kawaguchi, H. and Endo, T., Colloid Polym. Sci., 2007, 285: 873

    Article  CAS  Google Scholar 

  14. Huang, J., Huang, Z.M., Bao, Y.Z. and Weng, Z.X., Chinese J. Polym. Sci., 2006, 24(2): 195

    Article  CAS  Google Scholar 

  15. Song, H.Y., Liu, W.T., He, S.Q., Yang, M.C., Gao, Y., Zhu, C.S. and Wu, L.S., Chinese J. Polym. Sci., 2008, 26(2): 213

    Article  Google Scholar 

  16. Zhao, B. and Moore, J.S., Langmuir, 2001, 17: 4758

    Article  CAS  Google Scholar 

  17. Sun, J., Chen, J., Yang, L.M., Wang, S., Li, Z.J. and Wu, H.F., J. Biomater. Sci., Polym. Ed., 2007, 18(1): 35

    Article  CAS  Google Scholar 

  18. Ni, H., Kawaguchi, H. and Endo, T., Colloid Polym. Sci., 2007, 285: 819

    Article  CAS  Google Scholar 

  19. Zhang, X.Z., Zhang, J.T., Zhuo, R.X. and Chu, C.C., Polymer, 2002, 43: 4823

    Article  CAS  Google Scholar 

  20. Zhao, D.C., Liao, G.Z., Gao, G. and Liu, F.Q., Macromolecules, 2006, 39: 1160

    Article  CAS  Google Scholar 

  21. Li, W.B., Xue, F. and Cheng, R.S., Acta Polymeric Sinica(in Chinese), 2006, (5): 671

  22. Pal, K., Banthia, A.K. and Majumdar, D.K., Mater. Lett., 2008, 62: 215

    Article  CAS  Google Scholar 

  23. Liu, H.Q., Zhen, M. and Wu, R.H., Macromol. Chem. Phys., 2007, 208: 874

    Article  CAS  Google Scholar 

  24. Cao, S.G., Hu, B.H. and Liu, H.Q., Polym. Int., 2009, 58: 545

    Article  CAS  Google Scholar 

  25. Hou, D.D., Hao, T., Ye, L., Zhang, A.Y., Wang, C.Y. and Feng, Z.G., Acta Polymeric Sinica(in Chinese), 2008, (4): 388

  26. Jung, Y.P., Kim, J.H., Lee, D.S. and Kim, Y.H., J. Appl. Polym. Sci., 2007, 104: 2484

    Article  CAS  Google Scholar 

  27. Kavlak, S., Can, H.K., Rzaev, Z.M.O. and Guner, A., J. Appl. Polym. Sci., 2006, 100: 3926

    Article  CAS  Google Scholar 

  28. Can, H.K., Dogan, A.L., Rzaev, Z.M.O., Uner, A.H. and Guner, A., J. Appl. Polym. Sci., 2006, 100: 3425

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. College of Chemistry and Macdiarmid Laboratory, Jilin University, Changchun, 130012, China

    Meng Yang, Bo-tian Liu, Ge Gao, Xiao-li Liu & Feng-qi Liu  (刘凤岐)

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  1. Meng Yang
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  2. Bo-tian Liu
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  3. Ge Gao
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  4. Xiao-li Liu
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  5. Feng-qi Liu  (刘凤岐)
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Correspondence to Feng-qi Liu  (刘凤岐).

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Yang, M., Liu, Bt., Gao, G. et al. Poly(maleic anhydride-co-acrylic acid)/poly(ethylene glycol) hydrogels with pH- and ionic-strength-responses. Chin J Polym Sci 28, 951–959 (2010). https://doi.org/10.1007/s10118-010-9191-x

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  • DOI: https://doi.org/10.1007/s10118-010-9191-x

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