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The effect of low-level laser therapy on tooth movement during canine distalization

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Abstract

The aim of the study is to determine the effects of low level laser therapy on tooth movement during canine distalization by evaluating IL-1β, TGF-β1 levels in gingival crevicular fluid. Maxillary first premolars of the 15 Angle Class II division I patients (12–19 years old) were extracted. Right maxillary canines were distalized by standard protocol as control group whereas the left maxillary canines distalized by laser application. A gallium-aluminum-arsenide diode laser with an output power of 20 mW was applied as five doses from the buccal and the palatal side on the day 0, and the 3rd, 7th, 14th, 21th 30th, 33st, 37th, 60th, 63th, and 67th days. Gingival crevicular fluid samples were obtained with filtration paper at the initial, 7th, 14th, and 21th days, and the IL-1ß and TGF-ß1 cytokine levels were analyzed. Orthodontic models and periodontal indices were taken initially and on the days 30th, 60th, and 90th of canine distalization period. Tooth movement was assessed by scanning models (3Shape). The amount of tooth movement in the laser group was 40% more than the control group. First day IL-1ß levels were statistically higher than initial and 21st day levels (P= 0.003, P = 0.012). The rise in IL-1ß levels caused the negative correlations between 7th day IL-1β and 21st day TGF-β1 levels describes the tissue effects of laser application. Periodontal indices showed no sign of gingival inflammation during canine distalization period. As conclusion, laser does accelerate tooth movement and could shorten the whole treatment duration.

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Acknowledgements

This study was funded by the Research Fund of Istanbul University. Grant No. 40101 (Istanbul, Turkey).

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

The study protocol was approved by the Research Ethical Committee of Istanbul University (dated December 2013; internal code:1461/21).

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Authors and Affiliations

  1. Department of Orthodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey

    Sevin Erol Üretürk, Müyesser Saraç & Sönmez Fıratlı

  2. Department of Biochemistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey

    Şule Batu Can & Yegane Güven

  3. Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey

    Erhan Fıratlı

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  1. Sevin Erol Üretürk
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  2. Müyesser Saraç
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  3. Sönmez Fıratlı
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  4. Şule Batu Can
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Correspondence to Sevin Erol Üretürk.

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Üretürk, S.E., Saraç, M., Fıratlı, S. et al. The effect of low-level laser therapy on tooth movement during canine distalization. Lasers Med Sci 32, 757–764 (2017). https://doi.org/10.1007/s10103-017-2159-0

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  • DOI: https://doi.org/10.1007/s10103-017-2159-0

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