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Effects of diode laser (980 nm) on orthodontic tooth movement and interleukin 6 levels in gingival crevicular fluid in female subjects

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Abstract

The aim of this study was to evaluate the effects of low-level laser irradiation on the rate of orthodontic tooth movement (OTM) and the interleukin-6 (IL-6) concentration in gingival crevicular fluid (GCF) during orthodontic treatment. In this randomized split-mouth double blind clinical trial, 11 female patients aged 14 to 25 years (mean 19 ± 4.21 year), who required canine retraction following four first premolars extraction, were selected. The GaAlAs laser diode laser (A.R.C. Laser GmbH, Nürnberg, Germany) (980 nm, 100 mW, 5.6 J/cm2, three points from the buccal side and three from lingual side of the tooth, 56 s, running in continuous mode) was used for canine retraction in only one maxillary quadrant (LG). The irradiation time for each cervical and middle third of the tooth was 10 s, and 8 s for the apical third of the tooth. The other maxillary quadrant served as the control group (CG) using the laser pseudo-application in this side. The laser irradiation was applied on days 0, 7, 14, 21, and 28 of each month during the canine retraction phase. Canine retraction was done using closed coil spring with 150 g force on rectangular wires after the alignment and leveling. This study was done in 11 months. Dental casts were made at different time points during the treatment, and the amount of tooth movement was measured. To evaluate the levels of IL-6, GCF samples were collected from the distal side of the maxillary canine teeth on both quadrants at the beginning of the trial, the end of aligning phase, and on day 21 of each month during canine retraction. Although the mean rate of canine retraction was higher in the LG (0.013) than the CG (0.012) and there was definitely a tendency for more canine retraction in the LLLI, but the results failed to show any significant difference between the mean rate of canine retraction of both groups (P = 0.068). A paired t test showed that there was no significant difference in the mean concentration of IL-6 at various stages of the treatment between the groups during canine distalization (P > 0.05). Therefore, conclusive evidence could not be provided to support the efficacy of the diode laser (980 nm) in accelerating OTM in female subject.

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Acknowledgments

The authors gratefully acknowledge that this report is based on a thesis submitted to the School of Dentistry, Shahid Sadoughi University of Medical Sciences, in partial fulfillment of the requirement for a MS degree (grant No 3172). This study was financially supported and approved by the Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

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Authors and Affiliations

  1. Department of Orthodontics, Faculty of Dentistry, Shahid Sadoughi University of Medical Sciences, Daheye Fajr BLV, Imam Ave, Po Box:89195/165, Yazd, Iran

    S. Yassaei & H. Aghili

  2. Department of Allergy and Immunology, Immunology Research Center, Bu-Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    J. Tavakol Afshari

  3. Department of Oral and Maxillofacial Radiology, Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran

    A. Bagherpour

  4. Department of Orthodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    F. Eslami

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  1. S. Yassaei
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Correspondence to F. Eslami.

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Ethical standards

This clinical trial was verified by the ethical committee and the research vice chancellor of Shahid Sadoughi University of Medical Science by the P/17/1/31871 ethical code. All the patients or their parents signed informed consent.

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Yassaei, S., Aghili, H., Afshari, J.T. et al. Effects of diode laser (980 nm) on orthodontic tooth movement and interleukin 6 levels in gingival crevicular fluid in female subjects. Lasers Med Sci 31, 1751–1759 (2016). https://doi.org/10.1007/s10103-016-2045-1

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