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Docosahexaenoic acid production from crude glycerol by Schizochytrium limacinum SR21

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Abstract

In our search for a substitute energy source, microalgal biodiesel has presented itself as a potential candidate. However, the development of biodiesel results in the overproduction of crude glycerol, which can cause undesirable environmental issues. The environmental harm can be minimized by converting crude glycerol into value-added products. One solution involves using a microalga Schizochytrium limacinum SR21 to convert crude glycerol into docosahexaenoic acid (DHA). DHA is an essential fatty acid, necessary for developing brain functions in infants and maintaining healthy brain activity in adults. In our study, the highest DHA productivity of 233.73 mg/g biomass was obtained using 3 % crude glycerol in Medium 2 at 20 °C under mixo/heterotrophic cultivation.

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Acknowledgments

This work is supported financially by Fundamental Research Grant Scheme (Malaysia), Ministry of Science, Technology and Innovation (MOSTI-02-02-12-SF0256), and National Science Council (Taiwan, NSC102-2221-E-155-057 and NSC101-2632-E-155-001-MY3).

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Authors and Affiliations

  1. Biorefinery & Bioprocess Engineering Laboratory, Department of Chemical Engineering and Material Science, Yuan Ze University, No. 135 Yuan-Tung Road, Chungli, Taoyuan, 320, Taiwan

    Yun-Tsun Lung & John Chi-Wei Lan

  2. Department of Chemical and Environmental Engineering, Faculty of Engineering, University of Nottingham, Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia

    Chung Hong Tan, Pau Loke Show & Hon Loong Lam

  3. Manufacturing and Industrial Processes Division, Faculty of Engineering, Centre for Food and Bioproduct Processing, University of Nottingham, Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia

    Pau Loke Show

  4. Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Tau Chuan Ling

  5. Department of Chemical Engineering, National Cheng Kung University, Tainan, 701, Taiwan

    Jo-Shu Chang

  6. Research Center for Energy Technology and Strategy, National Cheng Kung University, Tainan, 701, Taiwan

    Jo-Shu Chang

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  1. Yun-Tsun Lung
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  2. Chung Hong Tan
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  3. Pau Loke Show
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  4. Tau Chuan Ling
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  5. John Chi-Wei Lan
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  6. Hon Loong Lam
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Correspondence to Pau Loke Show.

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Lung, YT., Tan, C.H., Show, P.L. et al. Docosahexaenoic acid production from crude glycerol by Schizochytrium limacinum SR21. Clean Techn Environ Policy 18, 2209–2216 (2016). https://doi.org/10.1007/s10098-016-1126-y

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  • DOI: https://doi.org/10.1007/s10098-016-1126-y

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