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Clinical features and outcome of community-onset bloodstream infections caused by extended-spectrum β-lactamase-producing Escherichia coli

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Abstract

This study was conducted to evaluate the epidemiology and clinical features of bloodstream infections caused by extended-spectrum β-lactamase-producing E. coli (ESBL-EC) in community-onset bacteremia. Of 929 episodes of community-onset E. coli bacteremia, 4.1% (38/929) had bacteremia with ESBL producers. Of these, 63.2% (24/38) were further classified as healthcare-associated infections. Although most patients had risk factors for infection due to ESBL producers, three patients with urinary tract infection, four patients with cholangitis, and one patient with a liver abscess had no identified predisposing risk factors. The 30-day mortality was 21.1% (8/38). ESBL-EC is a significant cause of bloodstream infection, even in patients with community-onset infection.

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Correspondence to K. R. Peck.

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C.I. Kang and H.S. Cheong contributed equally to the study.

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Kang, CI., Cheong, H.S., Chung, D.R. et al. Clinical features and outcome of community-onset bloodstream infections caused by extended-spectrum β-lactamase-producing Escherichia coli . Eur J Clin Microbiol Infect Dis 27, 85–88 (2008). https://doi.org/10.1007/s10096-007-0401-6

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  • DOI: https://doi.org/10.1007/s10096-007-0401-6

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