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Central pontine myelinolysis induced by hypophosphatemia following Wernicke’s encephalopathy

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Abstract.

A 62-year-old woman, after a resection and ileostomy for multiple perforations of the terminal ileum and prolonged postoperative parenteral nutrition, developed thiamine deficiency with clinical and magnetic resonance imaging features of Wernicke’s disease. Later on the patient developed central pontine myelinolysis. For this condition, a pathogenetic role of a transient hypophosphatemia was suggested by both laboratory data and course of the disease.

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Authors and Affiliations

  1. Belcolle Hospital, Viterbo, Italy

    N. Falcone & A. Nappo

  2. Medicine Department, Belcolle Hospital, Viterbo, Italy

    A. Compagnoni, C. Meschini & C. Perrone

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  1. N. Falcone
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  2. A. Compagnoni
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  3. C. Meschini
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  4. C. Perrone
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  5. A. Nappo
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Corresponding author

Correspondence to A. Nappo.

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Falcone, N., Compagnoni, A., Meschini, C. et al. Central pontine myelinolysis induced by hypophosphatemia following Wernicke’s encephalopathy. Neurol Sci 24, 407–410 (2004). https://doi.org/10.1007/s10072-003-0197-9

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  • DOI: https://doi.org/10.1007/s10072-003-0197-9

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