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Analgesic Effect of Intravenous Pamidronate on Chronic Back Pain due to Osteoporotic Vertebral Fractures

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Pamidronate, a bisphosphonate analogue has been evaluated in a retrospective study for its analgesic effect on chronic back pain due to vertebral fractures in 26 patients suffering from senile osteoporosis or glucocorticoid-induced osteoporosis. Sixty milligrams of pamidronate was administered intravenously every 3 months for one year. After three months of treatment, the pain score fell from 3.2 ± 0.1 to 1.2 ± 0.2 in both groups. In conclusion, intravenous pamidronate seems to be a valuable treatment for chronic back pain due to osteoporotic vertebral fractures.

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Received: 17 July 1998 / Accepted: 18 December 1998

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Gangji, V., Appelboom, T. Analgesic Effect of Intravenous Pamidronate on Chronic Back Pain due to Osteoporotic Vertebral Fractures. Clin Rheumatol 18, 266–267 (1999). https://doi.org/10.1007/s100670050099

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  • DOI: https://doi.org/10.1007/s100670050099

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