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Health-related quality of life in Moroccan patients with ankylosing spondylitis

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Abstract

The main objective of this study was to assess the aspects of health-related quality of life (QOL) in patients with ankylosing spondylitis (AS) and to explore the disease-related parameters influencing it. One hundred patients with AS according to New York Classification criteria were recruited in this cross-sectional study. The Medical Outcomes Study Short Form 36 Health Survey (SF-36) was used to assess health-related QOL. Assessment criteria included the evaluation of disease activity (Bath Ankylosing Spondylitis Disease Activity index [BASDAI]), global well-being (Bath Ankylosing Spondylitis Global Index [BASGI]), enthesitis (Mander enthesis index [MEI]), functional status (Bath Ankylosing Spondylitis Functional Index [BASFI]); metrology (Bath Ankylosing Spondylitis Metrology Index [BASMI]) and radiographic damage (Bath Ankylosing Spondylitis Radiologic Index [BASRI]). In this study, males comprised 67% of the subjects; mean age was 38 ± 13 years and mean disease duration was 9.5 ± 6.8 years. Among these patients, 52% had hip involvement. Our patients had a moderately active disease and severe functional disability. All domains of SF-36 were deteriorated with low scores. The SF-36 subgroups most affected were role limitation (18.8 ± 28.1), role emotional (19.4 ± 35), general health (44.9 ± 20.3) and vitality (38.0 ± 18.2). Lower scores of SF-36 had good statistically significant correlations with altered functional status (BASFI), worse general well-being (BASGI), altered metrology (BASMI); and moderate correlations with high disease activity (BASDAI), important radiological damage (BASRI); restricted chest expansion and prolonged morning stiffness (p < 0.001). This study states that health-related QOL in Moroccan patients with AS is damaged in a significant way. Mental as well as physical aspects were affected. Functional disability, patient’s well-being, metrology and disease activity are the main factors associated with deteriorating domains of QOL in AS. Recognizing complicated relationships between clinical measures and QOL in patients with AS can help us to develop further management strategies to improve their QOL.

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References

  1. Rugiene R, Kirdaite G, Gražuleviciute E, Dadoniene J, Venalis A (2008) The quality of life and functional ability in patients with ankylosing spondylitis. Acta Med Lituanica 15(2):99–103

    Google Scholar 

  2. Chorus AM, Miedema HS, Boonen A, van der Linden S (2003) Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age. Ann Rheum Dis 62(12):1178–1184

    Article  PubMed  CAS  Google Scholar 

  3. Dagfinrud H, Mengshoel AM, Hagen KB, Loge JH, Kvien TK (2004) Health status of patients with ankylosing spondylitis: a comparison with the general population. Ann Rheum Dis 63(12):1605–1610

    Article  PubMed  CAS  Google Scholar 

  4. The WOQOL Group (2000) What quality of life. World Health Forum 17:354–355

    Google Scholar 

  5. Schipper H, Clinch JJ, Olweny CLM (1996) Quality of life studies: definitions and conceptual issues. In: Spilker B (ed) Quality of life and pharmacoeconomics in clinical trials, 2nd edn. Lippincott-Raven Publishers, Philadelphia, pp 11–23

    Google Scholar 

  6. Moll JM (1987) New criteria for the diagnosis of ankylosing spondylitis. Scand J Rheumatol Suppl 65:12–24

    Article  PubMed  CAS  Google Scholar 

  7. Rostom S, Benbouazza K, Amine B, Bahiri R, Lazrak N, Abouqal R, Guillemin F, Hajjaj-Hassouni N (2009) Psychometric evaluation of the Moroccan version of the Bath Ankylosing Spondylitis Functional Index (BASFI) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) for use in patients with ankylosing spondylitis. Clin Rheumatol 2009 Nov;28. [Epub ahead of print]

  8. Haywood KL, Garratt AM, Jordan K, Dziedzic K, Dawes PT (2004) Spinal mobility in ankylosing spondylitis: reliability, validity and responsiveness. Rheumatology 43:750–757

    Article  PubMed  CAS  Google Scholar 

  9. Heuft-Dorenbosch L, Spoorenberg A, van Tubergen A, Landewe R, van der Tempel H, Mielants H, Dougados M, van der Heijde D (2003) Assessment of enthesitis in ankylosing spondylitis. Ann Rheum Dis 62(2):127–132

    Article  PubMed  CAS  Google Scholar 

  10. Ozer HTE, Sarpel T, Gulek BZ, Alparslan N, Erken E (2006) Evaluation of the Turkish version of the Bath Ankylosing Spondylitis Patient Global Score (BAS-G). Clin Rheumatol 25:136–139

    Article  PubMed  Google Scholar 

  11. Ward MM, Reveille JD, Learch TJ, Davis JC Jr, Weisman MH (2008) Occupational physical activities and long-term functional and radiographic outcomes in patients with ankylosing spondylitis. Arthritis Rheum 59(6):822–832

    Article  PubMed  Google Scholar 

  12. Khoudri I, Ali Zeggwagh A, Abidi K, Madani N, Abouqal R (2007) Measurement properties of the short form 36 and health-related quality of life after intensive care in Morocco. Acta Anaesthesiol Scand 51(2):189–197

    Article  PubMed  CAS  Google Scholar 

  13. Hays RD, Hahn H, Marshall G (2002) Use of the SF 36 and other health-related quality of life measures to assess persons with disabilities. Arch Phys Med Rehabil 83(Suppl 2):4–9

    Article  Google Scholar 

  14. Ware JE Jr, Kosinski M, Bayliss MS, McHorney CA, Rogers WH, Raczek A (1995) Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the medical outcomes study. Med Care 33(Suppl 4):264–279

    Google Scholar 

  15. Roussou E, Kennedyl G, Garrett S, Calin A (1997) Socioeconomic status in ankylosing spondylitis: Relationship between occupation and disease activity. J Rheumatol 24(5):979–1011

    Google Scholar 

  16. Ward MM (1999) Health-Related Quality of life in Ankylosing Spondylitis: a survey of 175 patients. Arthritis Care Res 12(4):247–255

    Article  PubMed  CAS  Google Scholar 

  17. Turan Y, Tuncay Duruöz M, Cerrahoglu L (2007) Quality of life in patients with ankylosing spondylitis: a pilot study. Rheumatol Int 27:895–899

    Article  PubMed  Google Scholar 

  18. Bostan EE, Borman P, Bodur H, Barca N (2003) Functional disability and quality of life in patients with ankylosing spondylitis. Rheumatol Int 23(3):121–126

    PubMed  Google Scholar 

  19. Ariza-Ariza R, Hernandez-Cruz B, Navarro-Sarabia F (2003) Physical function and health-related quality of life of Spanish patients with ankylosing spondylitis. Arthritis Rheum 49:483–487

    Article  PubMed  Google Scholar 

  20. Chorus AM, Miedema HS, Boonen A, Van Der Linden S (2003) Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age. Ann Rheum Dis 62:1178–1184

    Article  PubMed  CAS  Google Scholar 

  21. El Mansouri L, Bahiri R, Abourazzak FZ, Abouqal R, Hajjaj-Hassouni N (2009) Two distinct patterns of ankylosing spondylitis in Moroccan patients. Rheumatol Int 29:1423–1429

    Article  PubMed  Google Scholar 

  22. Auleley GR, Benbouazza K, Spoorenberg A, Collantes E, Hajjaj-Hassouni N, van der Heijde D, Dougados M (2002) Evaluation of the smallest detectable difference in outcome or process variables in ankylosing spondylitis. Arthritis Rheum 47(6):582–587

    Article  PubMed  Google Scholar 

  23. Vesovit-Potit V, Mustur D, Stanisavljevit D, Ille T, Ille M (2009) Relationship between spinal mobility measures and quality of life in patients with ankylosing spondylitis. Rheumatol Int 29(8):879–884

    Article  Google Scholar 

  24. Hamdi W, Azzouz D, Saadellaoui K, Daoud L, Kochbati S, Ben Hamida A, Zouari B, Kochir MM (2007) Correlations between Bath Ankylosing Spondylitis Metrology Index (BASMI), functional, structural, enthesopathy, disease activity index, and quality of life in 120 patients with ankylosing spondylitis. Ann Rheum Dis 66(Suppl II):398

    Google Scholar 

  25. Turan Y, Tuncay Duruöz T, Cerrahoglu L (2009) Relationship between enthesitis, clinical parameters and quality of life in spondyloarthritis. Jt Bone Spine, May 20 [Epub ahead of print]

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Authors and Affiliations

  1. Department of Rheumatology (Pr N. Hajjaj-Hassouni), El Ayachi Hospital, University Hospital of Rabat, Sale, 11000, Morocco

    Yousra Ibn Yacoub, Bouchra Amine, Assia Laatiris & Najia Hajjaj-Hassouni

  2. Laboratory of Biostatistics, Clinical Research and Epidemiology, Faculty of Medicine and Pharmacy, Rabat, Morocco

    Redouane Abouqal

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  1. Yousra Ibn Yacoub
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  2. Bouchra Amine
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  4. Redouane Abouqal
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  5. Najia Hajjaj-Hassouni
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Correspondence to Yousra Ibn Yacoub.

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Ibn Yacoub, Y., Amine, B., Laatiris, A. et al. Health-related quality of life in Moroccan patients with ankylosing spondylitis. Clin Rheumatol 30, 673–677 (2011). https://doi.org/10.1007/s10067-010-1613-1

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  • DOI: https://doi.org/10.1007/s10067-010-1613-1

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