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Association of complementary or alternative medicine use with quality of life, functional status or cumulated damage in chronic rheumatic diseases

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Abstract

Quality of life, functional status, or cumulated damage were compared between users and non-users of complementary and alternative medicine (CAM) in 445 rheumatic patients (rheumatoid arthritis [RA]: 64; systemic lupus erythematosus [SLE]: 192; fibromyalgia [FM]: 34; and knee osteoarthritis [KOA]: 155). CAM use was reported by 249 subjects (55.9%; 95%CI; 51.4–60.6). After a general linear model was applied, CAM use was associated with lower scores in the physical function (p = 0.02) and bodily pain (p = 0.03) domains of the SF-36 survey. In FM, RA and KOA, functional status was not different between users and non-users. CAM use was associated with higher cumulated damage (p = 0.04) in SLE. In patients with chronic rheumatic diseases, CAM use was not associated with better quality of life. Additionally, in SLE patients, CAM use was associated with higher cumulated damage. More research on CAM use in chronic rheumatic diseases is needed to better delineate its risk/benefit profile.

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References

  1. Nacional Center for Complementary and Alternative Medicine. National Institutes of Health. (2007) Available via: http://nccam.nih.gov/health/whatiscam/. Accessed 20 Sept 2007

  2. Eisenberg D, Kessler R, Van R, Kaptchuk T, Wilkey S, Appel S et al (2001) Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a National Survey. Ann Intern Med 135:344–351

    PubMed  CAS  Google Scholar 

  3. Eisenberg DM, Davis RB, Tener SL, Appel S, Wilkey S, van Rompay M et al (1998) Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey. JAMA 280:1569–1575

    Article  PubMed  CAS  Google Scholar 

  4. Desmet P (2002) Drug Therapy: herbal remedies. N Engl J Med 2002 2046–2056

  5. Rao JK, Mihaliak K, Kroenke K, Bradley J, Tierney W, Weinberger M (2003) Use of complementary therapies for arthritis among patients of rheumatologists. Ann Intern Med 131:409–416

    Google Scholar 

  6. Ernst E (2003) Complementary medicine. Curr Opin Rheumatol 15:151–155

    Article  PubMed  CAS  Google Scholar 

  7. Lau CS, Lo Y, Mok MY (2001) The use of complementary and alternative medicines in rheumatic diseases in Chinese. Arthritis Care Res 45:S13

    Google Scholar 

  8. Ramos-Remus C, Gamez-Nava JL, Gonzalez-López L et al (1998) Use of alternative therapies by patients with rheumatic diseases in Guadalajara, México: prevalence, believes and expectatives. Arthritis Care Res 11:411–418

    Article  PubMed  CAS  Google Scholar 

  9. Ramos-Remus C, Gutierrez-Urena S, Davis P (1999) Epidemiology of complementary and alternative practices in Rheumatology. Rheum Dis Clin North Am 25:789–804

    Article  PubMed  CAS  Google Scholar 

  10. Alvarez-Hernandez E, Casasola-Vargas JC, Lino-Perez L, Burgos-Vargas R, Vazquez-Mellado J (2006) Frecuencia de uso de medicinas complementarias y alternativas en sujetos que acuden por primera vez al servicio de reumatología. Análisis de 800 casos. [Frequency of use of complementary and alternative medicine in first-time patients of an outpatient rheumatology clinic. An analysis of 800 cases] [Spanish]. Reumatol Clin 2:183–189

    Article  Google Scholar 

  11. Leong KP, Pong LY, Chan SP (2003) Why lupus patients use alternative medicine. Lupus 12:659–664

    Article  PubMed  CAS  Google Scholar 

  12. Buchwald D (2003) Complementary and alternative medicine in fibromyalgia and related syndromes. Best Pract & Res Clin Rheumatol 17:667–683

    Article  Google Scholar 

  13. Weiner D, Edzards E (2004) Complementary and alternative approaches to the treatment of persistent musculoskeletal pain. Clin J Pain 20:244–255

    Article  PubMed  Google Scholar 

  14. Soeken K (2004) Selected CAM therapies for arthritis related pain: the evidence from systematic reviews. Clin J Pain 20:13–18

    Article  PubMed  Google Scholar 

  15. Reginster J-Y, Bruyere O, Neuprez A (2007) Current role of glucosamine in the treatment of osteoarthritis. Rheumatology (Oxford) 46:731–735

    Article  CAS  Google Scholar 

  16. Maheu E, Mazieres B, Valat JP et al (1998) Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. Arthritis Rheum 41:81–91

    Article  PubMed  CAS  Google Scholar 

  17. van Vollenhoven RF (2002) Dehydroepiandrosterone for the treatment of systemic lupus erythematosus. Expert Opin Pharmacother 3:23–31

    Article  PubMed  Google Scholar 

  18. Moore AD, Petri MA, Isenberg DA et al (2000) The use of alternative medical therapies in patients with systemic lupus erythematosus. Trination Study Group. Arthritis Rheum 43:1410–1418

    Article  PubMed  CAS  Google Scholar 

  19. Zochling J, March L, Lapsley H, Cross M, Tribe K, Brooks P (2004) Use of complementary medicines for osteoarthritis—a prospective study. Ann Rheum Dis 63:549–554

    Article  PubMed  CAS  Google Scholar 

  20. Ramos-Remus C, Gamez-Nava JI, Gonzalez-Lopez L, Suarez-Almazor ME (1997) Use of alternative medicine in a consecutive sample of patients with systemic lupus erythematosus. [Letter] J Rheumatol 4:2490–2491

    Google Scholar 

  21. Angell M, Kassirer JP (1998) Alternative medicine. The risk of untested and unregulated remedies. New Engl J Med 339:839–841

    Article  PubMed  CAS  Google Scholar 

  22. Arathi RS, Sigal LH (2005) Herbal medications commonly used in the practice of Rheumatology: mechanisms of action, efficacy and side effects. Semin Arthritis Rheum 34:773–784

    Article  Google Scholar 

  23. Hilepo JN, Belluci AG, Mossey RT (1997) Acute renal failure caused by “cat’s claw” herbal remedy in a patient with systemic lupus erythematosus. Nephron 77:361

    Article  PubMed  CAS  Google Scholar 

  24. Kraus A, Guerra-Bautista G, Alarcon-Segovia D (1991) Salmonella arizona arthritis and septicemia associated with rattlesnake ingestion by patients with connective tissue diseases. A dangerous complication of folk medicine. J Rheumatol 18:1328–1331

    PubMed  CAS  Google Scholar 

  25. Arnett FC, Edworthy SM, Bloch DA et al (1998) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315–324

    Article  Google Scholar 

  26. Wolfe F, Smythe HA, Yunus MB et al (1990) The American College of Rheumatology 1990. Criteria for the classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 33:160–172

    Article  PubMed  CAS  Google Scholar 

  27. Altman RD, Ash E, Bloch D et al (1986) Development of criteria for the classification and reporting of osteoarthritis of knee. Arthritis Rheum 29:1039–1049

    Article  PubMed  CAS  Google Scholar 

  28. Tan EM, Cohen AS, Fries JF et al (1982) The 1982 revised criteria for the classification for the Systemic Lupus erythematosus. Arthritis Rheum 25:1271–1277

    Article  PubMed  CAS  Google Scholar 

  29. The Medical Outcomes Trust: SF-36.org. Available at: http://www.sf-36.org/. Accessed 20 Sept 2007

  30. Zúñiga M, Carrillo-Jiménez GT, Fos PJ, Gandek B, Medina-Moreno MR (1999) Evaluación del estado de salud con la encuesta SF-36: resultados preliminares en México [Health status assessment using the SF-36 survey: preliminary results in Mexico] (Spanish) Salud Pública Mex 41:110–118

  31. Cardiel MH, Abello-Banfi M, Ruiz-Mercado R (1993) How to measure health status in rheumatoid arthritis in non-English speaking patients: validation of a Spanish version of the Health Assessment Questionnaire Disability Index (Spanish HAQ-DI). Clin Exp Rheumatol 11:117–121

    PubMed  CAS  Google Scholar 

  32. Burckhardt CS, Clark SR, Bennett RM (1991) The fibromyalgia impact questionnaire: development and validation. J Rheumatol 18:728–733

    PubMed  CAS  Google Scholar 

  33. Martínez-Rueda JO, Gonzalez-Sánchez CB, Hernández-Alonzo E (1995) Desarrollo y evaluación de la sensibilidad al cambio de una versión corta del Fibromyalgia Impact Questionnaire (FIQ). [Development and change sensitivity assessment of a short version of the Fibromyalgia Impact Questionnaire (FIQ)] (Spanish) Rev Mex Reumatol Suppl 1;P1

  34. Bellamy N, Buchanan WW, Goldsmith CH (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip and knee. J Rheumatol 15:1833–1840

    PubMed  CAS  Google Scholar 

  35. Gladman D, Ginzler E, Goldsmith C et al (1996) The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for Systemic Lupus Erythematosus. Arthritis Rheum 39:363–369

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

This research was partially funded by the 2005/1/I/196 FOFOI-IMSS Grant.

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Authors and Affiliations

  1. Unidad de Investigación Médica. Unidad Médica de Alta Especialidad. Instituto Mexicano del Seguro Social, Mérida, Yucatán, México

    José Alvarez-Nemegyei & Jorge Dávila-Velázquez

  2. Unidad de Medicina Familiar # 13. Delegación Yucatán. Instituto Mexicano del Seguro Social, Chuburná, Yucatán, México

    Alberta Bautista-Botello

  3. Calle 43 # 340 x 26 y 26-A, Fracc, Monte Albán, 97114, Merida, Yucatan, Mexico

    José Alvarez-Nemegyei

Authors
  1. José Alvarez-Nemegyei
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  2. Alberta Bautista-Botello
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  3. Jorge Dávila-Velázquez
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Correspondence to José Alvarez-Nemegyei.

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Alvarez-Nemegyei, J., Bautista-Botello, A. & Dávila-Velázquez, J. Association of complementary or alternative medicine use with quality of life, functional status or cumulated damage in chronic rheumatic diseases. Clin Rheumatol 28, 547–551 (2009). https://doi.org/10.1007/s10067-008-1082-y

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  • DOI: https://doi.org/10.1007/s10067-008-1082-y

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