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Mechanical circulatory support devices (MCSD) in Japan: current status and future directions

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Abstract

The current status and future directions of mechanical circulatory support devices (MCSDs) in Japan are reviewed. Currently used clinical MCSDs, both domestic and imported systems and continuous flow devices that are coming into the clinical arena are emphasized. Clinical MCSDs include the extracorporeal pulsatile Toyobo and Zeon systems and the implantable Novacor and HeartMate I VE. A thorough review is presented of single-ventricle continuous flow MCSDs such as the Terumo DuraHeart and the SunMedical EVAHEART and the biventricular Miwatec/Baylor systems that are on the horizon. The future directions in management of end-stage cardiac patients with MCSDs are discussed, focusing on (1) device selection – pulsatile versus continuous flow devices; (2) single-ventricle support, biventricular support, or replacement; (3) bridge to transplantation, destination therapy, or bridge to recovery; and (4) government regulatory processes and the medical industry. We hope to promote the quality of life (QOL) of end-stage cardiac patients as well as the medical industry in Japan.

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Authors and Affiliations

  1. Department of Artificial Organs, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-0062, Japan

    Setsuo Takatani PhD, DMed

  2. Osaka University, Suita, Osaka, Japan

    Hikaru Matsuda MD, PhD

  3. National Cardiovascular Center, Suita, Osaka, Japan

    Akihisa Hanatani MD, PhD

  4. Terumo Heart Inc., Ann Arbor, Michigan, USA

    Chisato Nojiri MD, PhD

  5. Tokyo Women’s Medical University, Tokyo, Japan

    Kenji Yamazaki MD, PhD

  6. Baylor College of Medicine, Houston, Texas, USA

    Tadashi Motomura MD, PhD

  7. Tokyo Medical and Dental University, Tokyo, Japan

    Katsuhiro Ohuchi MS & Tohru Sakamoto MD

  8. National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan

    Takashi Yamane PhD

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  1. Setsuo Takatani PhD, DMed
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  2. Hikaru Matsuda MD, PhD
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Correspondence to Setsuo Takatani PhD, DMed.

Additional information

This article is a summary review of the Rotary Blood Pump Symposium held on August 27, 2004, Tokyo, Japan

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Takatani, S., Matsuda, H., Hanatani, A. et al. Mechanical circulatory support devices (MCSD) in Japan: current status and future directions. J Artif Organs 8, 13–27 (2005). https://doi.org/10.1007/s10047-004-0284-6

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