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Combination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial

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Abstract

Objectives

This study evaluated the effect of photobiomodulation (PBM) combined with 8% strontium acetate (SA8%) in the treatment of dentin hypersensitivity (DH) in non-carious lesions and analyzed the risk factors with the patient’s quality of life.

Methods

Eighty teeth with DH were randomly allocated into four treatment groups (n = 20): G1, PBM imitation + toothpaste with no active ingredient; G2, PBM imitation + toothpaste with SA8%; G3, PBM + toothpaste without the active ingredient; and G4, PBM + toothpaste with SA8%. Participants were provided with a questionnaire on the experience of dentin hypersensitivity (QEDH) to assess the impact of desensitizing treatment on health-related quality of life (HRQL). Friedman and Kruskal–Wallis tests were used for intra- and intergroup comparisons, and Wilcoxon and Mann–Whitney tests were used to analyze HRQL. All analyses used significance levels of 5%.

Results

Intergroup comparisons revealed a significant difference (p < 0.05); G4 had the best response in terms of HD reduction in G4 compared to the other groups on the 7th day of assessment (T3). Only G4 showed a statistically significant difference (p < 0.05) in the reduction of EDH for intragroup analysis.

Conclusion

The combination of therapies was more effective in reducing DH than the isolated use of these strategies.

Clinical relevance

The combination of therapies is effective in the treatment of DH.

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Acknowledgements

We would like to thank the National Council for Scientific and Technological Development (CNPq/UFPA) for the subsidy provided that contributed to the purchase of the materials used in this study.

Funding

The work was supported by the National Council for Scientific and Technological Development (CNPq/UFPA).

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Correspondence to Cecy Martins Silva.

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Barros, A.P.O., de Melo Alencar, C., de Melo Pingarilho Carneiro, A. et al. Combination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial. Clin Oral Invest 26, 1299–1307 (2022). https://doi.org/10.1007/s00784-021-04104-2

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