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Efficacy of autogenous teeth for the reconstruction of alveolar ridge deficiencies: a systematic review

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Abstract

Aim

The aim of this systematic review was to critically evaluate the currently existing clinical evidence on the efficacy of autogenous teeth (AT) for the reconstruction of alveolar ridge deficiencies.

Materials and methods

A search protocol was developed to answer the focused question: “In patients exhibiting alveolar ridge deficiencies and being in need of an implant retained restoration, what is the efficacy of reconstructive procedures employing AT on changes in ridge dimensions compared with control measures?” Uncontrolled studies were also included to assess the overall efficacy of AT for specific procedures.

Results

A total of six studies (one randomized, one non-randomized controlled, two observational, one controlled case series, one retrospective) were identified. Two studies used AT for staged lateral augmentation, whereas four studies used AT as a demineralized dentin matrix (AutoBT) for the simultaneous grafting of dehiscence-type defects, vertical augmentation of post-extraction sockets, and lateral/transcrestal sinus floor elevation. The reported clinical outcomes following the application of either AT or AutoBT were within the range of those data noted in the respective control groups. Adverse events were commonly not observed.

Conclusions

The available limited studies involved relatively small patient samples and short follow-up periods but pointed to the potential of AT to serve as an alternative material for the reconstruction of alveolar ridge deficiencies.

Clinical relevance

AT appear to be effective in reconstructing alveolar ridge deficiencies.

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References

  1. Van der Weijden F, Dell'Acqua F, Slot DE (2009) Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol 36(12):1048–1058

    Article  PubMed  Google Scholar 

  2. Tan WL, Wong TL, Wong MC, Lang NP (2007) A systematic review of post-extractional alveolar hard and soft tissue dimensional changes in humans. Clin Oral Implants Res 23(5):1–21

    Google Scholar 

  3. McAllister BS, Haghighat K (2007) Bone augmentation techniques. J Periodontol 78(3):377–396

    Article  PubMed  Google Scholar 

  4. Jensen SS, Terheyden H (2009) Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different bone grafts and bone-substitute materials. Int J Oral Maxillofac Implants 24:218–236

    PubMed  Google Scholar 

  5. von Arx T, Cochran DL, Hermann JS, Schenk RK, Buser D (2001) Lateral ridge augmentation using different bone fillers and barrier membrane application. A histologic and histomorphometric pilot study in the canine mandible. Clin Oral Implants Res 12(3):260–269

    Article  Google Scholar 

  6. Sanz-Sanchez I, Carrillo de Albornoz A, Figuero E, Schwarz F, Jung R, Sanz M, Thoma D (2018) Effects of lateral bone augmentation procedures on peri-implant health or disease: a systematic review and meta-analysis. Clin Oral Implants Res 29(15):18–31

    Article  PubMed  Google Scholar 

  7. Chiriac G, Herten M, Schwarz F, Rothamel D, Becker J (2005) Autogenous bone chips: influence of a new piezoelectric device (Piezosurgery) on chip morphology, cell viability and differentiation. J Clin Periodontol 32(9):994–999

    Article  PubMed  Google Scholar 

  8. Cordaro L, Torsello F, Miuccio MT, di Torresanto VM, Eliopoulos D (2011) Mandibular bone harvesting for alveolar reconstruction and implant placement: subjective and objective cross-sectional evaluation of donor and recipient site up to 4 years. Clin Oral Implants Res 22(11):1320–1326

    Article  PubMed  Google Scholar 

  9. Roccuzzo M, Savoini M, Dalmasso P, Ramieri G (2017) Long-term outcomes of implants placed after vertical alveolar ridge augmentation in partially edentulous patients: a 10-year prospective clinical study. Clin Oral Implants Res 28(10):1204–1210

    Article  PubMed  Google Scholar 

  10. Nkenke E, Schultze-Mosgau S, Radespiel-Troger M, Kloss F, Neukam FW (2001) Morbidity of harvesting of chin grafts: a prospective study. Clin Oral Implants Res 12(5):495–502

    Article  PubMed  Google Scholar 

  11. Nkenke E, Neukam FW (2014) Autogenous bone harvesting and grafting in advanced jaw resorption: morbidity, resorption and implant survival. Eur J Oral Implantol 7(2):S203–S217

    PubMed  Google Scholar 

  12. Linde A (1989) Dentin matrix proteins: composition and possible functions in calcification. Anat Rec 224(2):154–166

    Article  PubMed  Google Scholar 

  13. Kim YK, Lee J, Um IW, Kim KW, Murata M, Akazawa T, Mitsugi M (2013) Tooth-derived bone graft material. J Korean Assoc Oral Maxillofac Surg 39(3):103–111

    Article  PubMed  PubMed Central  Google Scholar 

  14. Schwarz F, Golubovic V, Becker K, Mihatovic I (2016) Extracted tooth roots used for lateral alveolar ridge augmentation: a proof-of-concept study. J Clin Periodontol 43(4):345–353

    Article  PubMed  Google Scholar 

  15. Schwarz F, Golubovic V, Mihatovic I, Becker J (2016) Periodontally diseased tooth roots used for lateral alveolar ridge augmentation. A proof-of-concept study. J Clin Periodontol 43(9):797–803

    Article  PubMed  Google Scholar 

  16. Becker K, Drescher D, Honscheid R, Golubovic V, Mihatovic I, Schwarz F (2017) Biomechanical, micro-computed tomographic and immunohistochemical analysis of early osseous integration at titanium implants placed following lateral ridge augmentation using extracted tooth roots. Clin Oral Implants Res 28(3):334–340

    Article  PubMed  Google Scholar 

  17. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62(10):e1–e3

    Article  PubMed  Google Scholar 

  18. Hämmerle CH, Araújo MG, Simion M, Osteology Consensus Group 2011 (2011) Evidence-based knowledge on the biology and treatment of extraction sockets. Clin Oral Implants Res 23(5):641

    Google Scholar 

  19. Schwarz F, Hazar D, Becker K, Sader R, Becker J (2018) Efficacy of autogenous tooth roots for lateral alveolar ridge augmentation and staged implant placement. A prospective controlled clinical study. J Clin Periodontol. https://doi.org/10.1111/jcpe.12977

  20. Lee J-Y, Lee J, Kim Y-K (2013) Comparative analysis of guided bone regeneration using autogenous tooth bone graft material with and without resorbable membrane. J Dent Sci 8(3):281–286

    Article  Google Scholar 

  21. Jun SH, Ahn JS, Lee JI, Ahn KJ, Yun PY, Kim YK (2014) A prospective study on the effectiveness of newly developed autogenous tooth bone graft material for sinus bone graft procedure. J Adv Prosthodont 6(6):528–538

    Article  PubMed  PubMed Central  Google Scholar 

  22. Kim YK, Lee J, Yun JY, Yun PY, Um IW Comparison of autogenous tooth bone graft and synthetic bone graft materials used for bone resorption around implants after crestal approach sinus lifting: a retrospective study. J Periodontal Implant Sci 44(5):216–221

  23. Schwarz F, Sahin D, Becker K, Sader R, Becker J (2018) Autogenous tooth roots for lateral extraction socket augmentation and staged implant placement. A prospective observational study. Clin Oral Implants Res In Press (Ahead to Print)

  24. Pang KM, Um IW, Kim YK, Woo JM, Kim SM, Lee JH (2017) Autogenous demineralized dentin matrix from extracted tooth for the augmentation of alveolar bone defect: a prospective randomized clinical trial in comparison with anorganic bovine bone. Clin Oral Implants Res 28(7):809–815

    Article  PubMed  Google Scholar 

  25. Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 62(10):1006–1012

    Article  PubMed  Google Scholar 

  26. Kim YK, Lee JH, Um IW, Cho WJ (2016) Guided bone regeneration using demineralized dentin matrix: long-term follow-up. J Oral Maxillofac Surg 74(3):515.e1–515.e9

    Article  Google Scholar 

  27. Schwarz F, Schmucker A, Becker J (2016) Initial case report of an extracted tooth root used for lateral alveolar ridge augmentation. J Clin Periodontol 43(11):985–989

    Article  PubMed  Google Scholar 

  28. Pohl V, Pohl V, Schuh C, Fischer MB, Haas R (2016) A new method using autogenous impacted third molars for sinus augmentation to enhance implant treatment: case series with preliminary results of an open, prospective longitudinal study. Int J Oral Maxillofac Implants 31(3):622–630

    Article  PubMed  Google Scholar 

  29. Lee JY, Kim YK, Yi YJ, Choi JH (2013) Clinical evaluation of ridge augmentation using autogenous tooth bone graft material: case series study. J Korean Assoc Oral Maxillofac Surg 39(4):156–160

    Article  PubMed  PubMed Central  Google Scholar 

  30. Kim YK, Kim SG, Byeon JH, Lee HJ, Um IU, Lim SC, Kim SY (2010) Development of a novel bone grafting material using autogenous teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109(4):496–503

    Article  PubMed  Google Scholar 

  31. Kim YK, Kim SG, Um IW, Kim KW (2013) Bone grafts using autogenous tooth blocks: a case series. Implant Dent 22(6):584–589

    Article  PubMed  Google Scholar 

  32. Sung-Min Park I-WU, Kim K-W (2012) Clinical application of auto-tooth bone graft material. J Korean Assoc Oral Maxillofac Surg 2012(3):2–8

    Article  Google Scholar 

  33. Pohl V, Pohl V, Pohl S, Sulzbacher I, Fuerhauser R (2017) Alveolar ridge augmentation using dystopic autogenous tooth: 2-year results of an open prospective study. Int J Oral Maxillofac Implants 32(4):870–879

    Article  PubMed  Google Scholar 

  34. Minamizato T, Koga T, I T, Nakatani Y, Umebayashi M, Sumita Y, Ikeda T, Asahina I (2018) Clinical application of autogenous partially demineralized dentin matrix prepared immediately after extraction for alveolar bone regeneration in implant dentistry: a pilot study. Int J Oral Maxillofac Surg 47(1):125–132

    Article  PubMed  Google Scholar 

  35. Kim YK, Kim SG, Bae JH, Um IW, Oh JS, Jeong KI (2014) Guided bone regeneration using autogenous tooth bone graft in implant therapy: case series. Implant Dent 23(2):138–143

    Article  PubMed  Google Scholar 

  36. Kim YK, Yun PY, Um IW, Lee HJ, Yi YJ, Bae JH, Lee (2014) Alveolar ridge preservation of an extraction socket using autogenous tooth bone graft material for implant site development: prospective case series. J Adv Prosthodont 6(6):521–527

    Article  PubMed  PubMed Central  Google Scholar 

  37. Jeong KI, Kim SG, KimYK, Oh JS, Jeong MA, Park JJ (2011) Clinical study of graft materials using autogenous teeth in maxillary sinus augmentation. Implant Dent 20(6):471–475

    Article  PubMed  Google Scholar 

  38. Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, Carpenter JR, Chan AW, Churchill R, Deeks JJ, Hrobjartsson A, Kirkham J, Juni P, Loke YK, Pigott TD, Ramsay CR, Regidor D, Rothstein HR, Sandhu L, Santaguida PL, Schunemann HJ, Shea B, Shrier I, Tugwell P, Turner L, Valentine JC, Waddington H, Waters E, Wells GA, Whiting PF, Higgins JP (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919. https://doi.org/10.1136/bmj.i4919

    Article  PubMed  PubMed Central  Google Scholar 

  39. von Arx T, Buser D (2006) Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. Clin Oral Implants Res 17(4):359–366

    Article  Google Scholar 

  40. Acocella A, Bertolai R, Colafranceschi M, Sacco R (2010) Clinical, histological and histomorphometric evaluation of the healing of mandibular ramus bone block grafts for alveolar ridge augmentation before implant placement. J Craniomaxillofac Surg 38(3):222–230

    Article  PubMed  Google Scholar 

  41. Barbu HM, Andreescu CF, Lorean A, Kolerman R, Moraru L, Mortellaro C, Mijiritsky E (2016) Comparison of two techniques for lateral ridge augmentation in mandible with ramus block graft. J Craniofac Surg 27(3):662–667

    Article  PubMed  Google Scholar 

  42. Widmark G, Ivanoff CJ (2000) Augmentation of exposed implant threads with autogenous bone chips: prospective clinical study. Clin Implant Dent Relat Res 2(4):178–183

    Article  PubMed  Google Scholar 

  43. von Arx T, Kurt B (1999) Implant placement and simultaneous ridge augmentation using autogenous bone and a micro titanium mesh: a prospective clinical study with 20 implants. Clin Oral Implants Res 10(1):24–33

    Article  Google Scholar 

  44. Chen ST, Darby IB, Adams GG, Reynolds EC (2005) A prospective clinical study of bone augmentation techniques at immediate implants. Clin Oral Implants Res 16(2):176–184

    Article  PubMed  Google Scholar 

  45. Zijderveld SA et al Long-term changes in graft height after maxillary sinus floor elevation with different grafting materials: radiographic evaluation with a minimum follow-up of 4.5 years. Clin Oral Implants Res 20(7):691–700

  46. Schmitt C, Karasholi T, Lutz R, Wiltfang J, Neukam FW, Schlegel KA (2014) Long-term changes in graft height after maxillary sinus augmentation, onlay bone grafting, and combination of both techniques: a long-term retrospective cohort study. Clin Oral Implants Res 25(2):e38–e46

    Article  PubMed  Google Scholar 

  47. Kahnberg KE, Wallstrom M, Rasmusson L (2011) Local sinus lift for single-tooth implant. I: clinical and radiographic follow-up. Clin Implant Dent Relat Res 13(3):231–237

    Article  PubMed  Google Scholar 

  48. Nishida T, Takenouchi Y, Mori K, Ariji M, Nishida K, Ito K (2013) Remodeling of autogenous bone grafts after osteotome sinus floor elevation assessed by limited cone beam computed tomography. Int J Dent 2013:931708

    Article  PubMed  PubMed Central  Google Scholar 

  49. Cordaro L, Torsello F, Morcavallo S, di Torresanto VM (2011) Effect of bovine bone and collagen membranes on healing of mandibular bone blocks: a prospective randomized controlled study. Clin Oral Implants Res Res 22(10):1145–1150

    Article  Google Scholar 

  50. Penarrocha-Diago M, Aloy-Prosper A, Penarrocha-Oltra D, Calvo-Guirado JL, Penarrocha-Diago M (2013) Localized lateral alveolar ridge augmentation with block bone grafts: simultaneous versus delayed implant placement: a clinical and radiographic retrospective study. Int J Oral Maxillofac Implants 28(3):846–853

    Article  PubMed  Google Scholar 

  51. De Stavola L, Tunkel J (2013) A new approach to maintenance of regenerated autogenous bone volume: delayed relining with xenograft and resorbable membrane. Int J Oral Maxillofac Implants 28(4):1062–1067

    Article  PubMed  Google Scholar 

  52. Valderrama P, Oates TW, Jones AA, Simpson J, Schoolfield JD, Cochran DL (2007) Evaluation of two different resonance frequency devices to detect implant stability: a clinical trial. J Periodontol 78(2):262–272

    Article  PubMed  Google Scholar 

  53. Kuchler U, Chappuis V, Bornstein MM, Siewczyk M, Gruber R, Maestre L, Buser D (2017) Development of implant stability quotient values of implants placed with simultaneous sinus floor elevation—results of a prospective study with 109 implants. Clin Oral Implants Res 28(1):109–115

    Article  PubMed  Google Scholar 

  54. Danesh-Sani SA, Wallace SS, Movahed A, El Chaar ES, Cho SC, Khouly I, Testori T (2016) Maxillary sinus grafting with biphasic bone ceramic or autogenous bone: clinical, histologic, and histomorphometric results from a randomized controlled clinical trial. Implant Dent 25(5):588–593

    Article  PubMed  Google Scholar 

  55. Schmitt CM, Doering H, Schmidt T, Lutz R, Neukam FW, Schlegel KA (2013) Histological results after maxillary sinus augmentation with Straumann(R) BoneCeramic, Bio-Oss(R), Puros(R), and autologous bone. A randomized controlled clinical trial. Clin Oral Implants Res 24(5):576–585

    Article  PubMed  Google Scholar 

  56. Saltaji H, Armijo-Olivo S, Cummings GG, Amin M, da Costa BR, Flores-Mir C (2018) Impact of selection bias on treatment effect size estimates in randomized trials of oral health interventions: a meta-epidemiological study. J Dent Res 97(1):5–13

    Article  PubMed  Google Scholar 

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Funding

This study was funded by the authors’ own departments.

Author information

Authors and Affiliations

  1. Department of Oral Surgery and Implantology, Carolinum, Goethe University, Frankfurt, Germany

    Ausra Ramanauskaite & F. Schwarz

  2. Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

    Ausra Ramanauskaite, D. Sahin & J. Becker

  3. Department for Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Medical Center of the Goethe University Frankfurt, Frankfurt am Main, Germany

    R. Sader

Authors
  1. Ausra Ramanauskaite
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  2. D. Sahin
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  3. R. Sader
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  4. J. Becker
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  5. F. Schwarz
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Correspondence to Ausra Ramanauskaite.

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Appendix

Appendix

Table 5 Literature search strategies
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Table 6 List of studies excluded by title and abstract (n = 234)
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Ramanauskaite, A., Sahin, D., Sader, R. et al. Efficacy of autogenous teeth for the reconstruction of alveolar ridge deficiencies: a systematic review. Clin Oral Invest 23, 4263–4287 (2019). https://doi.org/10.1007/s00784-019-02869-1

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  • DOI: https://doi.org/10.1007/s00784-019-02869-1

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