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Fluoride releasing and enamel demineralization around orthodontic brackets by fluoride-releasing composite containing nanoparticles

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Abstract

Introduction

Fluoride-containing materials have been suggested to control enamel demineralization around orthodontic brackets during the treatment with fixed appliances. The improvement of their properties has been made through innovations, such as the application of nanotechnology by incorporation of nanofillers.

Objective

This in vitro study evaluated the capacity of fluoride releasing and enamel demineralization inhibition of fluoride-releasing nanofilled cement around orthodontic brackets using an artificial caries biofilm model.

Materials and methods

Forty bovine enamel discs were selected by evaluating surface microhardness and randomized into four groups (n = 10): non-fluoride-releasing microfilled composite, fluoride-releasing microfilled composite, resin-modified glass ionomer cement (RMGI), and fluoride-releasing nanofilled composite (FN). After brackets bonding in each disc, the specimens were subjected to a cariogenic challenge through a Streptococcus mutans biofilm model. After the experimental period, the biofilm formed around the brackets was collected for fluoride analysis and the mineral loss around the brackets was determined by integrated demineralization via cross-sectional microhardness measurement at 20 and 70 μm from the bracket margin. Additionally, samples of each group were subjected to energy-dispersive X-ray spectroscopy (EDX) analysis examined under a scanning electron microscopy (SEM). ANOVA followed by Tukey test were applied for fluoride concentration and mineral loss data, respectively.

Results

At both distances, only RMGI statistically differed from the other groups presenting the lowest demineralization, although there was a trend to a lower demineralization of enamel around brackets in FN group. Similar condition was found to fluoride concentration and EDX/SEM analysis.

Conclusions

Under the cariogenic exposure condition of this study, the fluoride-releasing nanofilled material had similar performance to fluoride-releasing microfilled materials.

Clinical relevance

The presence of nanofillers in the fluoride-releasing materials studied did not promote further benefits against caries lesion development around brackets and presented inferior demineralization inhibition than the resin-modified glass ionomer material.

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Acknowledgments

The authors gratefully thank José Júnior da Alves da Silva for his assistance with SEM/EDX analysis and Institute of Research, Development and Innovation (IPDI) for providing the SEM equipment. The first and second authors have received scholarships during this study from CNPq (#141791/2010-1) and CNPq/PIBIC/UFC, respectively.

Conflict Of Interest Statement

None declared.

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Authors and Affiliations

  1. Post-graduate Program in Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, 944 Cap Francisco Pedro Street—Rodolfo Teófilo, Fortaleza, Ceará, 60430-170, Brazil

    Mary A. S. Melo, Weslanny A. Morais, Juliana P. M. Lima & Lidiany K. A. Rodrigues

  2. School of Dentistry, University of Fortaleza, Washington Soares Avenue,1321, Fortaleza, Ceará, 60811-905, Brazil

    Vanara F. Passos

Authors
  1. Mary A. S. Melo
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  2. Weslanny A. Morais
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  3. Vanara F. Passos
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  4. Juliana P. M. Lima
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  5. Lidiany K. A. Rodrigues
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Corresponding author

Correspondence to Lidiany K. A. Rodrigues.

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Melo, M.A.S., Morais, W.A., Passos, V.F. et al. Fluoride releasing and enamel demineralization around orthodontic brackets by fluoride-releasing composite containing nanoparticles. Clin Oral Invest 18, 1343–1350 (2014). https://doi.org/10.1007/s00784-013-1073-5

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  • DOI: https://doi.org/10.1007/s00784-013-1073-5

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