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Thermodynamic and Kinetic Studies on Reactions of Pt(II) Complexes with Pyrazole, Pyridazine, and 1,2,4-Triazole

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Summary.

Substitution reactions of the complexes [Pt(dien)H2O]2+ and [PtCl(dien)]+, where dien = diethylentriamine or 1,5-diamino-3-azapentane, with some nitrogen-donor ligands such as 1,2,4-triazole, pyrazole, and pyridazine, were studied in an aqueous 0.10 M NaClO4 at pH = 2.5 using variable-temperature spectrophotometry and 1H NMR spectroscopy. The second-order rate constants indicate that the aqua complex, [Pt(dien)H2O]2+, is more reactive than the corresponding chloro complex, [PtCl(dien)]+. The reactivity of the used ligands follows the order: 1,2,4-triazole > pyridazine > pyrazole. Activation parameters were determined for all reactions and the negative entropies of activation (ΔS ≠) support an associative ligand substitution mechanism.

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References

  • T Soldatović ŽD Bugarčić (2005) J Inorg Biochem 99 1472 Occurrence Handle10.1016/j.jinorgbio.2005.04.005

    Article  Google Scholar 

  • BV Petrović ŽD Bugarčić (2005) Aust J Chem 58 544 Occurrence Handle10.1071/CH05033

    Article  Google Scholar 

  • V Vasić M Živanović M Čakar J Savić J Nedeljković ŽD Bugarčić (2005) J Phys Org Chem 1 441 Occurrence Handle10.1002/poc.880

    Article  Google Scholar 

  • Bugarčić ŽD, Heinemann FW, van Eldik R (2004) Dalton Trans 279

  • Bugarčić ŽD, Soldatović T, Jelić R, Alguero B, Grandas A (2004) Dalton Trans 3869

  • ŽD Bugarčić D Jančić AA Shoukry MM Shoukry (2004) Monatsh Chem 135 151

    Google Scholar 

  • (a) Reedijk J, Teuben MJ (1999) In: Lippert B (ed) Cisplatin Chemistry and Biochemistry of Leading Anticancer Drugs, Wiley-VCH, Zürich, pp 339–362 (b) Reedijk J (1999) Chem Rev 99: 2467 (c) Jamieson ER, Lippard SJ (1999) Chem Rev 99: 2467 (d) Jakupec MA, Galanski M, Keppler BK (2003) Rev Phisiol Biochem Pharmaco 146: 1 (e) Wong E, Grandomenico CM (1999) Chem Rev 99: 2451

  • Bugarčić ŽD, Liehr G, van Eldik R (2002) J Chem Soc Dalton Trans 951

  • Bugarčić ŽD, Liehr G, van Eldik R (2002) J Chem Soc Dalton Trans 2825

  • RJ Sundberg RB Martin (1974) Chem Rev 74 471 Occurrence Handle10.1021/cr60290a003 Occurrence Handle1:CAS:528:DyaE2cXltFKjs7o%3D

    Article  CAS  Google Scholar 

  • CA Hitchcock (1991) Biochem Soc Trans 19 782 Occurrence Handle1:CAS:528:DyaK3MXkvVClurc%3D

    CAS  Google Scholar 

  • RW Taft F Anvia M Taagepera J Catalan J Elguero (1986) J Am Chem Soc 108 3237 Occurrence Handle10.1021/ja00272a013 Occurrence Handle1:CAS:528:DyaL28XktVKisr4%3D

    Article  CAS  Google Scholar 

  • M Meot-Ner (1988) J Am Chem Soc 110 3071 Occurrence Handle10.1021/ja00218a013

    Article  Google Scholar 

  • J Catalan J Elguero (1983) J Chem Soc Perkin Trans 2 1869

    Google Scholar 

  • MH Ibraham PP Duce DV Prior DG Barratt JJ Morris PJ Taylor (1989) J Chem Soc Perkin Trans 2 1355

    Google Scholar 

  • Bugarčić ŽD, Nandibewoor ST, Hamza MSA, Heinemann F, van Eldik R (2006) Dalton Trans 2984

  • ML Tobe J Burgess (1999) Inorganic Reaction Mechanisms Addison Wesley Longman Inc. Essex 74

    Google Scholar 

  • M Kotowski R van Eldik (1986) NoChapterTitle R van Eldik (Eds) Inorganic High-Pressure Chemistry: Kinetics and Mechanisms, Ch 4 Elsevier Amsterdam

    Google Scholar 

  • JA Joule GF Smith (1972) Heterocyclic Chemistry Chapman and Hall London

    Google Scholar 

  • G Annibale M Brandolisio B Pitteri (1995) Polyhedron 14 451 Occurrence Handle10.1016/0277-5387(94)00408-7 Occurrence Handle1:CAS:528:DyaK2MXktlCrs7Y%3D

    Article  CAS  Google Scholar 

  • TGA Appleton RJ Hall SF Ralph CSM Thompson (1984) Inorg Chem 23 3521 Occurrence Handle10.1021/ic00190a017 Occurrence Handle1:CAS:528:DyaL2cXlvValt7s%3D

    Article  CAS  Google Scholar 

  • ŽD Bugarčić BV Petrović R Jelic (2001) Trans Met Chem 26 668 Occurrence Handle10.1023/A:1012064512961

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac, Serbia

    Jovana Rosić, Biljana Petrović, Miloš I. Djuran & Živadin D. Bugarčić

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  1. Jovana Rosić
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  2. Biljana Petrović
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  3. Miloš I. Djuran
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  4. Živadin D. Bugarčić
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Correspondence to Živadin D. Bugarčić.

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Rosić, J., Petrović, B., Djuran, M. et al. Thermodynamic and Kinetic Studies on Reactions of Pt(II) Complexes with Pyrazole, Pyridazine, and 1,2,4-Triazole. Monatsh. Chem. 138, 1–11 (2007). https://doi.org/10.1007/s00706-006-0568-z

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  • DOI: https://doi.org/10.1007/s00706-006-0568-z

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