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Human bocavirus 2 detected in Rattus norvegicus feces in China

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Abstract

Bocaviruses are typical zoonotic pathogens with a wide range of hosts. Here, we report the detection of human bocavirus (HBoV) in Rattus norvegicus captured in China and the results of sequencing and phylogenetic analysis based on the partial VP1 region and the entire viral genome. A total of 357 fecal samples from rats were collected in 2015-2017 and analyzed for HBoV using PCR. The detection rate of HBoV was 0.84% (3/357). Phylogenetic analysis revealed that this virus is genetically closely related to HBoV-2. R. norvegicus may be a carrier of HBoV, and its impact on public health merits attention.

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Fig. 1
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Data availability

All data generated or analyzed during this study are included in this published article. Access to raw data can be acquired by contacting the corresponding author via email.

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Acknowledgements

We sincerely appreciate the contribution to this paper made by my teammates concerning the sample collection and technical assistance.

Funding

This work was supported by the National Natural Science Foundation of China (81973107).

Author information

Author notes

  1. Fang-Fei You and Min-Yi Zhang contributed to the work equally and should be regarded as co-first authors.

Authors and Affiliations

  1. Department of Epidemiology, School of Public Health, Guangdong Provincial Key Laboratory of Tropical Disease Research, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, China

    Fang-Fei You, Min-Yi Zhang, Fei Wu, Qiu-Shuang Li & Qing Chen

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  1. Fang-Fei You
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  2. Min-Yi Zhang
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  3. Fei Wu
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Contributions

Conceptualization: FFY, MYZ. Methodology: FW. Formal analysis: MYZ. Investigation: QSL, FW. Writing (original draft preparation): FFY, MYZ. Writing (review and editing): QC. Supervision: QC.

Corresponding author

Correspondence to Qing Chen.

Ethics declarations

Ethical approval

The study protocol was approved by the Animal Ethics and Welfare Committee of the School of Public Health of Southern Medical University (Guangzhou, China) and adhered to the guidelines for the Rules for the Implementation of Laboratory Animal Medicine (1998) from the Ministry of Health (Beijing, China). Endangered or protected species were not involved in this study.

Conflict of interest

The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Handling Editor: Ana Cristina Bratanich.

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You, FF., Zhang, MY., Wu, F. et al. Human bocavirus 2 detected in Rattus norvegicus feces in China. Arch Virol 167, 171–175 (2022). https://doi.org/10.1007/s00705-021-05274-w

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  • DOI: https://doi.org/10.1007/s00705-021-05274-w

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