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Prevalence of hepatitis B virus genotypes in chronic carriers in Santiago, Chile

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Abstract

The eight genotypes (designated A–H) of hepatitis B virus (HBV) display distinctive geographical distribution worldwide, with genotypes A, D and F frequently detected in South America. To determine the prevalence of HBV genotypes in Santiago, Chile, 131 samples from chronic carriers were used for PCR amplification, and genotyping was performed by RFLP. The results indicated that genotype F was the most prevalent among HBV carries (84% of the cases), whereas genotypes A, B, C and D were found at a prevalence of 3.8, 3.8, 6.1, and 2.3%, respectively. We discuss these data in the complex scenario of HBV epidemiology.

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Acknowledgments

We thank GlaxoSmithKline Chile Farmacéutica Ltda.

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Authors and Affiliations

  1. Sección de Gastroenterología, Departamento de Medicina, Hospital Clínico de la Universidad de Chile, Av. Santos Dumont 999, Independencia, Santiago, Chile

    Mauricio Venegas, Gabriela Muñoz, Carmen Hurtado, Luis Alvarez, Marta Velasco & Javier Brahm

  2. Programa de Virología, Instituto de Ciencias Biomédicas, Escuela de Medicina, Universidad de Chile, Av. Independencia 1027, Independencia, Santiago, Chile

    Rodrigo A. Villanueva

Authors
  1. Mauricio Venegas
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  2. Gabriela Muñoz
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  3. Carmen Hurtado
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  4. Luis Alvarez
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  5. Marta Velasco
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  6. Rodrigo A. Villanueva
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  7. Javier Brahm
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Correspondence to Mauricio Venegas.

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Venegas, M., Muñoz, G., Hurtado, C. et al. Prevalence of hepatitis B virus genotypes in chronic carriers in Santiago, Chile. Arch Virol 153, 2129–2132 (2008). https://doi.org/10.1007/s00705-008-0231-6

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  • DOI: https://doi.org/10.1007/s00705-008-0231-6

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