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A carbon paste electrode modified with a cobalt(II) coordination polymer for the direct voltammetric determination of tryptophan

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Abstract

We have synthesized a cobalt(II) coordination polymer and have characterized it by various methods including X-ray single crystal structural analysis. The polymer was used as modifier to fabricate a carbon paste electrode that displays electrochemical activity towards tryptophan (Trp). Trp is oxidized at the surface of the electrode in buffer solution of pH 4.2, yielding a single peak at 814 mV. The experimental conditions such as the concentration, the composition and the pH values of the supporting electrolyte, accumulation time, and the scan rate were optimized. Under the optimized conditions, the current of peak is linearly related to the concentration of Trp in the range from 0.2 to 8.0 μM, and from 8.0 to 80.0 μM. The detection limit (at S/N = 3) is 0.1 μM at an accumulation time of 60 s. The determination of Trp in amino acid injection solutions was evaluated and the results were satisfactory. The recoveries were in the range of 97.5% to 103.0%.

As shown in Fig. 1, a well-defined and very sharp oxidation peak at 814 mV was obtained in the curve the curve b. Whereas, a relatively weak anodic peak at 835 mV can be observed under the same conditions with an bare electrode. By comparing curve b and c, it can be seen that, the peak current was about 0.720 μA with the bare CPE. However, the peak current was increased to 10.39 μA with the modified CPE. This significant improvement of peak current may be related to the effective catalytic fashion of the cobalt (II) coordination polymer film modified on the surface of the CPE in the electrochemical oxidation of Trp.

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Acknowledgement

This work was supported by the Fund of Hunan Provincial Natural Science Foundation of China (No. 11JJ9006 and 10JJ3024), Science and Technology Committee of Hunan Province (No. 2009FJ3101 and 2011FJ3037), Science and Technology Committee of Hengyang (No. 2011kj25) and the Construct Program of the Key Discipline in Hunan Province.

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Authors and Affiliations

  1. Department of Chemistry and Material Science, Hengyang Normal University, Hengyang, 421008, China

    Wei Li, Yunfei Kuang, Peihong Deng, Shaohua Zhang & Jinsheng Xu

  2. Department of Material and Chemical Engineering, Hunan Institute of Technology, Hengyang, 421002, China

    Changhong Li

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  1. Wei Li
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  2. Changhong Li
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  3. Yunfei Kuang
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  4. Peihong Deng
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  5. Shaohua Zhang
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Correspondence to Wei Li or Changhong Li.

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Li, W., Li, C., Kuang, Y. et al. A carbon paste electrode modified with a cobalt(II) coordination polymer for the direct voltammetric determination of tryptophan. Microchim Acta 176, 455–461 (2012). https://doi.org/10.1007/s00604-011-0740-y

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  • DOI: https://doi.org/10.1007/s00604-011-0740-y

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