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Carbon paste electrode modified with a binuclear manganese complex as a sensitive voltammetric sensor for tryptophan

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Abstract

We report on a carbon paste electrode that was modified with a binuclear manganese(II) complex by the drop-coating method. A study on the mechanism of the electro-oxidation of tryptophan (Trp) at this electrode indicated that it enables Trp to be determined with good sensitivity and selectivity. Second-order derivative linear sweep voltammetry at pH 4.1 revealed that a sensitive anodic peak appears at 812 mV (vs. SCE) whose current is proportional to the concentration of Trp in the concentration range from 0.1 to 1.0 μmol L−1 and 1.0 to 80 μmol L−1, with a detection limit (S/N = 3) of 0.08 μmol L−1 (60 s of accumulation). The method was applied to the determination of Trp in amino acid injection solutions with satisfactory results.

The electrochemical behavior of tryptophan at a carbon paste electrode modified with a binuclear manganese(II) complex Mn2(phen)2(p-MBA)4(H2O) was investigated. The modified electrode showed high electrocatalytic activity toward the oxidation of tryptophan and the peak current increases linearly with tryptophan concentration in the range of 0.1 to 80 μmol L−1.

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Acknowledgement

This work was supported by Natural Science Foundation of Hunan Province of China (No.10JJ3024), the Project of Science and Technology Bureau of Hengyang City (No. 2010KJ21) and the Construct Program of the Key Discipline in Hunan Province.

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Authors and Affiliations

  1. Department of Chemistry and Material Science, Hengyang Normal University, Hengyang, 421008, China

    Jinsheng Xu, Wei Li & Peihong Deng

  2. College of Chemistry and Chemical Engineering, Nanhua University, Hengyang, 421001, China

    Yali Yuan & Jian Deng

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  1. Jinsheng Xu
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  2. Yali Yuan
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  3. Wei Li
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  4. Peihong Deng
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  5. Jian Deng
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Correspondence to Jinsheng Xu or Peihong Deng.

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Xu, J., Yuan, Y., Li, W. et al. Carbon paste electrode modified with a binuclear manganese complex as a sensitive voltammetric sensor for tryptophan. Microchim Acta 174, 239–245 (2011). https://doi.org/10.1007/s00604-011-0619-y

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  • DOI: https://doi.org/10.1007/s00604-011-0619-y

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