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Electrochemical sensor for procaine based on a glassy carbon electrode modified with poly-amidosulfonic acid and multi-walled carbon nanotubes

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Abstract

A glassy carbon electrode was prepared that was coated with a composite film containing electropolymerized poly(amidosulfonic acid) and multi-walled carbon nanotubes. It was used to study the electrochemical response of procaine by differential pulse voltammetry. The results indicate that the electrode exhibits a remarkable improvement in the oxidation peak of procaine, and this led to a simple and sensitive method for the electroanalytical determination of procaine. The peak current is proportional to the concentration of procaine from 80 nM to 1.0 µM. The detection limit is 25 nM (S/N = 3). The modified electrode was successfully applied to the direct determination of procaine in pharmaceutical formulations.

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Acknowledgements

This work was financially supported by Natural Science Foundation of Hubei province (2008CDB034) and the Foundation of Hubei Provincial Department of Education for Young Scholars (Q20081006).

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Authors and Affiliations

  1. Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, People’s Republic of China

    Xiuhua Zhang, Dongming Zhao, Lijun Feng, Li Jia & Shengfu Wang

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  1. Xiuhua Zhang
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  2. Dongming Zhao
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  3. Lijun Feng
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  4. Li Jia
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  5. Shengfu Wang
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Correspondence to Shengfu Wang.

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Zhang, X., Zhao, D., Feng, L. et al. Electrochemical sensor for procaine based on a glassy carbon electrode modified with poly-amidosulfonic acid and multi-walled carbon nanotubes. Microchim Acta 169, 153–159 (2010). https://doi.org/10.1007/s00604-010-0330-4

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  • DOI: https://doi.org/10.1007/s00604-010-0330-4

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