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Survival benefit of lateral lymph node dissection according to the region of involvement and the number of lateral lymph nodes involved

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Abstract

Purpose

The effectiveness of lateral lymph node dissection for extending the survival of patients with advanced lower rectal cancer remains unclear. The purpose of this study was to clarify the survival benefit of lateral lymph node dissection according to the region of involvement and the number of lateral lymph nodes involved.

Methods

We reviewed 131 consecutive patients with advanced lower rectal cancer, who had undergone curative resection with total mesorectal excision plus extended lateral lymph node dissection at Wakayama Medical University Hospital. Twenty-six (19.1 %) of these patients had lateral lymph involvement. We performed univariate and multivariate analyses for the 3-year disease-free and overall survival of these patients.

Results

Multivariate analysis revealed that the number (>1) and the region (common iliac artery region or external iliac artery region) of lateral lymph node metastasis are independent predictive factors for recurrence and survival. The Kaplan–Meier analysis demonstrated that patients with one lymph node metastasis in the internal iliac artery or obturator region had better survival.

Conclusions

Lateral lymph node dissection resulted in survival benefit for patients with single lateral lymph node involvement in the internal iliac artery region or the obturator region.

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Conflict of interest

have no potential conflicts of interest to disclose.

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Authors and Affiliations

  1. Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8510, Japan

    Shozo Yokoyama, Katsunari Takifuji, Tsukasa Hotta, Kenji Matsuda, Takashi Watanabe, Yasuyuki Mitani, Junji Ieda & Hiroki Yamaue

Authors
  1. Shozo Yokoyama
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  2. Katsunari Takifuji
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  3. Tsukasa Hotta
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  4. Kenji Matsuda
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  5. Takashi Watanabe
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  6. Yasuyuki Mitani
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  7. Junji Ieda
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  8. Hiroki Yamaue
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Correspondence to Hiroki Yamaue.

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Yokoyama, S., Takifuji, K., Hotta, T. et al. Survival benefit of lateral lymph node dissection according to the region of involvement and the number of lateral lymph nodes involved. Surg Today 44, 1097–1103 (2014). https://doi.org/10.1007/s00595-013-0815-y

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  • DOI: https://doi.org/10.1007/s00595-013-0815-y

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