Abstract
Twenty-one patients with back pain originating from the endplate injuries were selected to explore the methods of diagnosis and surgical treatment. All patients underwent examinations using radiography, CT, and MR imaging. Pain level of disc was determined through discography in each patient. The principal outcome judgments were pain and disability, and the efficacy of surgical treatment was assessed through the use of the visual analog scale (VAS) for pain and the Oswestry disability index (ODI) for functional recovery. All 21 patients with a diagnosis of back pain originating from endplate injuries according to discography were treated with anterior or posterior fusion surgery. The mean follow-up period was 3 years and 5 months (range, 2–6 years). Of the 21 patients, 20 (20/21) reported a disappearance or marked alleviation of low back pain and experienced a definite improvement in physical function. Statistically significant and clinically meaningful improvements in the VAS and ODI scores were obtained after treatment in the patients with chronic low back pain originating from the endplate injuries (P = 0.0001). The study suggests that discography and fusion surgery may be very effective methods for the diagnosis and treatment, respectively, of chronic back pain originating from the endplate injuries.
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Aggrawal ND, Kaur R, Kumar S, Mathur DN (1979) A study of changes in the spine in weight lifters and other athletes. Br J Sports Med 13:58–61. doi:10.1136/bjsm.13.2.58
Andersson GB (1999) Epidemiologic features of chronic low-back pain. Lancet 354:581–585. doi:10.1016/S0140-6736(99)01312-4
Brown MF, Hukkanen MVJ, McCarthy ID et al (1997) Sensory and sympathetic innervation of the vertebral endplate in patients with degenerative disc disease. J Bone Joint Surg Br 79:147–153. doi:10.1302/0301-620X.79B1.6814
Carragee EJ (2005) Persistent low back pain. N Engl J Med 352:1891–1898. doi:10.1056/NEJMcp042054
Chandraraj S, Briggs CA, Opeskin K (1998) Disc herniations in the young and endplate vascularity. Clin Anat 11:171–176. doi:10.1002/(SICI)1098-2353(1998)11:3<171::AID-CA4>3.0.CO;2-W
Deyo RA, Weinstein JN (2001) Low back pain. N Engl J Med 344:363–370. doi:10.1056/NEJM200102013440508
de Roos A, Kresse H, Spritzer C et al (1987) MR imaging of marrow changes adjacent to endplates in degenerative lumbar disc disease. AJR Am J Roentgenol 149:531–534
Fahey V, Opeskin K, Silberstein M, Anderson R, Briggs C (1998) The pathogenesis of Schmorl’s nodes in relation to acute trauma: an autopsy study. Spine 23:2272–2275. doi:10.1097/00007632-199811010-00004
Fairbank JC, Couper J, Davies JB et al (1980) The Oswestry low back pain disability questionnaire. Physiotherapy 66:271–273
Fritzell P, Hagg O, Wessberg P, Nordwall A (2006) The Swedish Lumbar Spine Study Group. 2001 Volve award winner in clinical studies: lumbar fusion versus nonsurgical treatment for chronic low back pain. A multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine 23:2521–2534
Fritzell P, Hagg O, Wessberg P et al (2002) Chronic low back pain and fusion: a comparison of three surgical techniques: a prospective multicenter randomized study from the Swedish lumbar spine study group. Spine 27:1131–1141. doi:10.1097/00007632-200206010-00002
Heggeness MH, Doherty BJ (1993) Discography causes end plate deflection. Spine 18:1050–1053
Hanley EN, David SM (1999) Lumbar arthrodesis for the treatment of back pain. J Bone Joint Surg Am 81:716–730
Hauger O, Cotton A, Chateil JF et al (2001) Giant cystic Schmorl’s nodes: imaging findings in six patients. AJR Am J Roentgenol 176:969–972
Kokkonen S, Kurunlahti M, Tervonen O et al (2002) Endplate degeneration observed on magnetic resonance imaging of the lumbar spine: correlation with pain provocation and disc changes observed on computed tomography diskography. Spine 27:2274–2278. doi:10.1097/00007632-200210150-00017
Lee CK, Vessa P, Lee JY (1995) Chronic disabling low back pain syndrome caused by internal disc derangements. The results of disc excision and posterior lumbar interbody fusion. Spine 20:356–361
Lotz JC, Ulrich JA (2006) Innervation, inflammation, and hypermobility may characterize pathologic disc degeneration: review of animal model data. J Bone Joint Surg Am 88(suppl 2):76–82. doi:10.2106/JBJS.E.01448
Modic MT, Masaryk TJ, Ross JS et al (1988) Imaging of degenerative disk disease. Radiology 168:177–186
Modic MT, Steinberg PM, Ross JS et al (1988) Degenerative disc disease: assessment of changes in vertebral body marrow with MRI imaging. Radiology 166:194–199
Moore KR, Pinto MR, Butler LM (2002) Degenerative disc disease treated with combined anterior and posterior arthrodesis and posterior instrumentation. Spine 27:1680–1686. doi:10.1097/00007632-200208010-00018
Peng B, Hao J, Hou S et al (2006) Possible pathogenesis of painful intervertebral disc degeneration. Spine 31:560–566. doi:10.1097/01.brs.0000201324.45537.46
Peng B, Wu W, Hou S, Li P, Zhang C, Yang Y (2005) The pathogenesis of discogenic low back pain. J Bone Joint Surg Br 87:62–67
Peng B, Wu W, Hou S, Shang W, Wang X, Yang Y (2003) The pathogenesis of Schmorl’s nodes. J Bone Joint Surg Br 85:879–882
Penta M, Fraser RD (1997) Anterior lumbar interbody fusion. A minimum 10-year follow-up. Spine 22:2429–2434. doi:10.1097/00007632-199710150-00021
Resnick DK (2003) Spinal Fusion for Discogenic back pain: patient selection, operative techniques, and outcomes. Tech Neurosurg 8:176–190. doi:10.1097/00127927-200308030-00006
Saluja G, Fitzpatrick K, Bruce M, Cross J (1986) Schmorl’s nodes (intravertebral herniations of intervertebral disc tissue) in two historic British populations. J Anat 145:87–96
Takahashi K, Miyazaki T, Ohnari H et al (1995) Schmorl’s nodes and low-back pain: analysis of magnetic resonance imaging findings in symptomatic and asymptomatic individuals. Eur Spine J 4:56–59. doi:10.1007/BF00298420
Takahashi K, Takiata K (1994) A large painful Schmorl’s node: a case report. J Spinal Disord 7:77–81. doi:10.1097/00002517-199407010-00011
Wagner AL, Murtagh R, Arrington JA et al (2000) Relationship of Schmorl’s nodes to vertebral body endplate fractures and acute endplate disk extrusions. AJNR Am J Neuroradiol 21:276–281
Walters G, Coumas JM, Akins CM, Ragland RL (1991) Magnetic resonance imaging of acute symptomatic Schmorl’s node formation. Pediatr Emerg Care 7:294–296. doi:10.1097/00006565-199110000-00009
Yasuma T, Saito S, Kihara K (1988) Schmorl’s nodes: correlation of X-ray and histological findings in postmortem specimens. Acta Pathol Jpn 38:723–733
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Supported by the Foundation of capital medical development, Beijing, China. The funding sources had no involvement or influence in the preparation of the manuscript.
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Peng, B., Chen, J., Kuang, Z. et al. Diagnosis and surgical treatment of back pain originating from endplate. Eur Spine J 18, 1035–1040 (2009). https://doi.org/10.1007/s00586-009-0938-4
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DOI: https://doi.org/10.1007/s00586-009-0938-4