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The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2

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Abstract

FKBP-rapamycin associated protein (FRAP) is a phosphatidylinositol kinase (PIK)-related kinase implicated in the inhibition of progression through G1 of the cell cycle. The PIK-related kinases are a growing family of proteins involved in cell-cycle checkpoints, DNA repair and recombination. We have mapped the human FRAP gene to chromosome 1p36.2, a region consistently deleted in neuroblastomas.

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Authors and Affiliations

  1. Molecular Medicine Unit, University of Leeds, Clinical Sciences Building, St. James’s University Hospital, Leeds LS9 7TF, UK Tel.: +44-113-283-7078; Fax: +44-113-244-4475 e-mail: desnl@stjames.leeds.ac.uk, , , , , , GB

    N. J. Lench, Robert Macadam & Alexander F. Markham

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  1. N. J. Lench
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  2. Robert Macadam
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  3. Alexander F. Markham
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Received: 6 August 1996

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Lench, N., Macadam, R. & Markham, A. The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2. Hum Genet 99, 547–549 (1997). https://doi.org/10.1007/s004390050404

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  • DOI: https://doi.org/10.1007/s004390050404

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