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Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

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Abstract.

The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsa-stained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immunocapture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.

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Authors and Affiliations

  1. Department of Clinical Pathology, Capital Armed Forces General Hospital, 13–4, San, Yul Dong, BunDang Gu, SungNam City, Kyunggi Province, Republic of Korea, 157–032, , , , ,

    Duck Cho

  2. Department of Internal Medicine, Korea University Anam Hospital, 126–1, 5 Ga, Anam Dong, Sungbuk Gu, Seoul, Republic of Korea, 136–705, , , , ,

    Kwang Kim & Seung Park

  3. Department of Clinical Pathology, Korea University Anam Hospital, 126–1, 5 Ga, Anam Dong, Sungbuk Gu, Seoul, Republic of Korea, 136–705, , , , ,

    Young Kim

  4. Department of Clinical Pathology, Korea University Guro Hospital, 80, Guro Dong, Guru Gu, Seoul, Republic of Korea, 152–703, , , , ,

    Kap Lee

  5. Department of Clinical Pathology, College of Medicine, Korea University Ansan Hospital, 516, Gojan Dong, Ansan City, Kyunggi Province, Republic of Korea, 425-020, , , , ,

    Chae Lim

Authors
  1. Duck Cho
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  2. Kwang Kim
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  3. Seung Park
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  4. Young Kim
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  5. Kap Lee
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  6. Chae Lim
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Cho, D., Kim, K., Park, S. et al. Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea. Parasitol Res 87, 445–448 (2001). https://doi.org/10.1007/s004360000360

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  • DOI: https://doi.org/10.1007/s004360000360

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