Abstract
The survival of skin penetrating cercariae depends on information on the direction to move toward deeper layers in the epidermis (the direction of further migration) and toward the surface (direction which must be avoided when migrating). We tested the hypothesis that parasites can use their photo-sensitivity for orientation away from the light-exposed skin surface towards darker locations. Cercariae of species invading humans (Schistosoma mansoni), birds (Trichobilharzia ocellata) and fish (Diplostomum spathaceum) oriented towards light sources when free swimming in cuvettes. However, they shifted to a negative photo-orientation when migrating in agar substrates after penetration and transformation to schistosomula. This is a first hint that parasites may use photo-orientation when they navigate in host tissues.
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References
Feiler W, Haas W (1988a) Host-finding in Trichobilharzia ocellata cercariae: swimming and attachment to the host. Parasitology 96:493–505
Feiler W, Haas W (1988b) Trichobilharzia ocellata: chemical stimuli of duck skin for cercarial attachment. Parasitology 96:507–517
Haas W (1969) Reizphysiologische Untersuchungen an Cercarien von Diplostomum spathaceum. Z Vergl Physiol 64:254–287
Haas W (1974) Analyse der Invasionsmechanismen der Cercarie von Diplostomum spathaceum. II. Chemische Invasionsstimuli. Int J Parasitol 4:321–330
Haas W (1992) Physiological analysis of cercarial behavior. J Parasitol 78:243–255
Haas W (1994) Physiological analyses of host-finding behaviour in trematode cercariae: adaptations for transmission success. Parasitology 109:S15–S29
Haas W, Haberl B (1997) Host recognition by trematode miracidia and cercariae. In: Fried B, Graczyk TK (eds) Advances in trematode biology. CRC Press, Boca Raton, pp 197–227
Haas W, van de Roemer A (1998) Invasion of the vertebrate skin by cercariae of Trichobilharzia ocellata: penetration processes and stimulating cues. Parasitol Res 84:787–795
Haas W, Grabe K, Geis C, Päch T, Stoll K, Fuchs M, Haberl B, Loy C (2002a) Recognition and invasion of human skin by Schistosoma mansoni cercariae: the key-role of l-arginine. Parasitology 124:153–167
Haas W, Stiegeler P, Keating A, Kullmann B, Rabenau H, Schönamsgruber E, Haberl B (2002b) Diplostomum spathaceum cercariae respond to a unique profile of cues during recognition of their fish host. Int J Parasitol 32:1145–1154
Loy C, Motzel W, Haas W (2001) Photo- and geo-orientation by echinostome cercariae results in habitat selection. J Parasitol 87:505–509
Neuhaus W (1952) Biologie und Entwicklung von Trichobilharzia szidati n. sp. (Trematoda, Schistosomatidae), einem Erreger von Dermatitis beim Menschen. Z Parasitenkd 15:203–266
Niewiadomska K (1984) Present status of Diplostomum spathaceum (Rudolphi, 1819) and differentiation of Diplostomum pseudospathaceum nom. nov. (Trematoda: Diplostomatidae). Syst Parasitol 6:81–86
Niewiadomska K, Kiseliene V (1994) Diplostomum cercariae (Digenea) in snails from Lithuania. II. Survey of species. Acta Parasitol 39:179–186
Odening K (1996) What Cercaria ocellata actually is? In: Özcel MA (ed) New dimensions in parasitology. Acta Parasitol Turcica [Suppl 1]:387–397
Saladin KS (1982) Schistosoma mansoni: cercarial responses to irradiance changes. J Parasitol 68:120–124
Shiff CJ, Cmelik SH, Ley HE, Kriel RL (1972) The influence of human skin lipids on the cercarial penetration responses of Schistosoma haematobium and Schistosoma mansoni. J Parasitol 58:476–80
Short RB, Gagné HT (1975) Fine structure of a possible photoreceptor in cercariae of Schistosoma mansoni. J Parasitol 61:69–74
Smyth JD, Halton DW (1983) The physiology of trematodes, 2nd edn. Cambridge University Press, Cambridge
Sopott-Ehlers B, Haas W, Ehlers U (2003) Ultrastructure of pigmented and unpigmented photoreceptors in cercariae of Trichobilharzia ocellata (Plathelminthes, Trematoda, Schistosomatidae): evidence for the evolution of parasitism in Neodermata. Parasitol Res 91:109–116
Sukhdeo MVK, Sukhdeo SC (1994) Optimal habitat selection by helminths within the host environment. Parasitology 109:S41–S55
Sukhdeo MVK, Sukhdeo SC (2002) Fixed behaviours and migration in parasitic flatworms. Int J Parasitol 32:329–342
Van de Roemer A, Haas W (1984) Fine structure of a lens-covered photoreceptor in the cercaria of Trichobilharzia ocellata. Z Parasitenkd 70:391–394
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This work was supported by the Deutsche Forschungsgemeinschaft. The experiments comply with the current laws of Germany.
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Grabe, K., Haas, W. Navigation within host tissues: cercariae orientate towards dark after penetration. Parasitol Res 93, 111–113 (2004). https://doi.org/10.1007/s00436-003-1045-9
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DOI: https://doi.org/10.1007/s00436-003-1045-9