Skip to main content
Log in

One-lung flooding for video-assisted thoracoscopic surgery in animal experiments on pigs — oxygenation and intrapulmonary shunt

  • Published:
Research in Experimental Medicine

Abstract

Unilateral flooding of the lung after intubation with a double-lumen tube makes intraoperative sonography of the lung during video-assisted thoracoscopic surgery possible. After flooding with 15 ml/kg, the arterial partial oxygen pressure (with FiO2=1.0) is higher than that in total atelectasis by about 100 mmHg, while it is only slightly less than that during bilateral lung ventilation. Compared to total atelectasis, lung flooding reduces the pulmonary right-to-left shunt volume. The pulmonary function normalizes within 8 h after the operation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Aguinaga G, Santos P, Renes E, Alvaro PF, Lorente JA, Maudes A, Diaz RR, Landin L, Liste D (1991) Hemodynamic changes during whole bronchoalveolar lavage in two cases of pulmonary alveolar proteinosis. Intensive Care Med 17:421–423

    Article  CAS  PubMed  Google Scholar 

  2. Benumof JL (1986) Isoflurane anesthesia and arterial oxygenation during one-lung ventilation. Anesthesiology 64:419–422

    Article  CAS  PubMed  Google Scholar 

  3. Carlsson AJ, Bindslev L, Hedenstierna G (1987) Hypoxia-induced vasoconstriction in the human lung. The effect of isoflurane anesthesia. Anesthesiology 66:312–316

    Article  CAS  PubMed  Google Scholar 

  4. Cohen E, Eisenkraft JB (1990) Bronchopulmonary lavage: effects on oxygenation and hemodynamics. J Cardiothorac Anesth 4:609–615

    Article  CAS  PubMed  Google Scholar 

  5. Danel C, Israel-Biet U, Costabel U, Klech H (1992) Therapeutic applications of bronchoalveolar lavage. Eur Respir J 5:1173–1175

    CAS  PubMed  Google Scholar 

  6. Groh J, Kuhnle GEH, Ney L, Sckell A, Geotz AE (1995) Effects of isoflurane on regional pulmonary blood flow during one-lung ventilation. Br J Anaesth 74:209–216

    Article  CAS  PubMed  Google Scholar 

  7. Hemstad JR, Spiess BD, Marchioro TL, Raghu G (1994) Pulmonary artery and non-invasive hemodynamics during lung lavage in primary alveolar proteinosis. Chest 105:1605–1608

    Article  CAS  PubMed  Google Scholar 

  8. Jedeikin R, Olsfanger D, Shachor D (1994) Intraoperative anaesthetic management of hypoxaemia during transthoracic endoscopic sympathectomy. Eur J Surg 160: [Suppl 572]23–25

    Google Scholar 

  9. Lesser T, Klinzing S, Schubert J, Klein U, Bartel M (1999) Lung flooding — a new method for complete lung sonography. Res Exp Med 198:83–91

    Article  Google Scholar 

  10. Lesser T, Klinzing S, Schubert J, Bartel M (1999) Simulations of lung lesions for validating the sonography of the flooded lung. Res Exp Med 198:261–268

    Article  CAS  Google Scholar 

  11. Ramirez RJ, Kieffer R, Ball W (1965) Broncho-bronchopulmonary lavage in man. Ann Intern Med 63:819–828

    Article  CAS  PubMed  Google Scholar 

  12. Shapiro BA (1988) Arterial blood gas monitoring. In: Vender JS (ed) Symposium on Intensive Care Monitoring, Critical Care Clinics 4, no 3. Saunders, Philadelphia pp 479–484

    Google Scholar 

  13. Tate K, Zoellner P, Bode E T (1992) Bronchopulmonary lavage for pulmonary Alveolar proteinosis. Missouri Med 89:27–30

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Klinzing.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Klinzing, S., Lesser, T., Schubert, H. et al. One-lung flooding for video-assisted thoracoscopic surgery in animal experiments on pigs — oxygenation and intrapulmonary shunt. Res. Exp. Med. 199, 333–340 (1999). https://doi.org/10.1007/s004339900043

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004339900043

Key words

Navigation