Skip to main content
Log in

Cardiovascular risk factors in children and adolescents living in an urban area of Southeast of Brazil: Ouro Preto Study

  • Original Paper
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

This study aims to identify risk factors for cardiovascular disorders in schoolchildren living in Ouro Preto City, Brazil. A cross-sectional study was carried out in a population-based sampling of schoolchildren (6–14 years old), randomly selected and stratified by the proportion of students according to age and gender in each schools of the city. Biochemical, clinical and anthropometric variables as well as physical activity and family history were used in a logistic regression model for obesity or arterial hypertension. Out of 780 schoolchildren sampled, the risk of obesity was greater in subjects presenting high triglyceride and low high density lipoprotein-cholesterol levels, and those whose parents were obese, whilst the risk of hypertension was high in obese subjects and those who presented low birth weight. It was observed that 44.4% of the schoolchildren were exposed to two or three cardiovascular disease (CVD) risk factors and 8.2% were exposed to four or six factors. These findings should be considered in preventive measures to reduce the future risk for CVD among schoolchildren in Brazil.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Abrantes MM, Lamounier JA, Colosimo EA (2003) Prevalência de sobrepeso e obesidade nas regiões Nordeste e Sudeste do Brasil. Rev Assoc Med Bras 49:162–166

    Article  PubMed  Google Scholar 

  2. Barlassina C, Lanzani C, Manunta P, Bianchi G (2002) Genetics of essential hypertension: from families to genes. J Am Soc Nephrol 13:S155–S164

    Article  PubMed  CAS  Google Scholar 

  3. Berenson GS, Srnivasan SR (2005) Cardiovascular risk factors in youth with implications for aging: the Bogalusa heart study. Neurobiol Aging 26:303–307

    Article  PubMed  CAS  Google Scholar 

  4. Botton J, Heud B, Kettaneh A et al (2007) Cardiovascular risk factor levels and their relationships with overweight and fat distribution in children: the Fleurbaix Laventie Ville Sante´ II study. Metabolism 56:614–622

    Article  PubMed  CAS  Google Scholar 

  5. Bouchard C (1997) Genetic determinants of regional fat distribution. Hum Reprod 12:1–5

    Article  PubMed  Google Scholar 

  6. Cândido APC, Ferreira S, Lima AA et al (2007) Lipoprotein(a) as a risk factor associated with ischemic heart disease: Ouro Preto study. Atherosclerosis 191:454–459

    Article  PubMed  Google Scholar 

  7. Clarke WR, Schrott HG, Leaverton PE et al (1978) Tracking of blood lipids and blood pressures in school age children: the Muscatine study. Circulation 58:626–634

    PubMed  CAS  Google Scholar 

  8. Centers for Disease Control. National Center for Health Statistics and the National Center for Chronic Disease Prevention and Health Promotion, CDC Growth Charts: Available at: http://www.cdc.gov/growthcharts. Accessed 19 Oct 2006

  9. Centers for Disease Control and Prevention. Physical activity and the health of young people. Division of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion. Available at: http://www.cdc.gov/healthyyoung/physicalactivity. Accessed 28 Jul 2006

  10. Centers for Disease Control and Prevention. Reducing children’s TV time to reduce the risk of childhood overweight: the children’s media use study. Report highlights. Available at: http://www.cdc.gov/nccdphp/dnpa/obesity/pdf/TV_Time_Highligts.pdf. Accessed 3 Dec 2007

  11. Chen W, Srinivasan SR, Li S et al (2007) Clustering of long-term trends in metabolic syndrome variables from childhood to adulthood in blacks and whites. The Bogalusa Heart Study. Am J Epidemiol 166:527–533

    Article  PubMed  Google Scholar 

  12. DATASUS. Mortalidade no município de Ouro Preto/MG. Caderno de informação de saúde. Available at: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sih/cnv/miMG.def. Accessed 10 Jun 2008)

  13. DATASUS. Taxa de mortalidade específica por doenças do aparelho circulatório. Indicadores e dados básicos no Brasil. Available at: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?idb2002/c08.def. Accessed 10 Jun 2008

  14. Demory-Luce D, Morales M, Nicklas T et al (2004) Changes in food group consumption patterns from childhood to young adulthood: the Bogalusa heart study. J Am Diet Assoc 104:1684–1691

    Article  PubMed  Google Scholar 

  15. Falker B (2002) Birth weight as a predictor of future hypertension. Am J Hypertens 15:S43–S45

    Article  Google Scholar 

  16. Franca E, Alves JGB (2006) Dislipidemia entre crianças e adolescentes de Pernambuco. Arq Bras Cardiol 87:722–727

    Article  PubMed  Google Scholar 

  17. Freedman DS, Mei Z, Srinivasan SR et al (2007) Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa heart study. J Pediatr 150:12–17

    Article  PubMed  Google Scholar 

  18. Freitas SN, Caiaffa WT, César CC et al (2007) A comparative study of methods for diagnosis of obesity in urban mixed-race population in Minas Gerais. Brazil Public Health Nutr 10:883–890

    Google Scholar 

  19. Galeazzi MA, Domene SM, Schieri R. Estudo multicêntrico sobre consumo de alimentos. Available at: http://www.unicamp.br/nepa/arquivo_san/cadernosespecial.pdf. Accessed 3 Dec 2007)

  20. Gidding SS, Barton BA, Dorgan JA et al (2006) Higher self-reported physical activity is associated with lower systolic blood pressure: the Dietary Intervention Study in Childhood (DISC). Pediatrics 118:2388–2393

    Article  PubMed  Google Scholar 

  21. Giuliano ICB, Caramelli B, Pellanda L et al (2005) Diretriz de prevenção da aterosclerose na infância e adolescência. Arq Bras Cardiol 85(Supl.VI):1–36

    Google Scholar 

  22. Giuliano ICB, Coutinho MSSA, Freitas SFT et al (2005) Lípides séricos em crianças e adolescentes de Florianópolis, SC–Estudo Floripa saudável 2040. Arq Bras Cardiol 85:85–91

    Article  Google Scholar 

  23. Goodman E, Dolan LM, Morrison JA, Daniels SR (2005) Factor analysis of clustered cardiovascular risks in adolescence. Obesity is the predominant correlate of risk among youth. Circulation 111:1970–1977

    Article  PubMed  Google Scholar 

  24. Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira. Matrícula no ensino fundamental no município de Ouro Preto, Minas Gerais. Available at: http://www.edudatabrasil.inep.gov.br/index.htm. (Accessed in 15 Sept 2008)

  25. Kay JD, Sinaiko AR, Daniels SR (2001) Pediatric hypertension. Am Heart J 142:422–432

    Article  PubMed  CAS  Google Scholar 

  26. Kelley C, Krummel D, Gonzales EN et al (2004) Dietary intake of children at high risk for cardiovascular disease. J Am Diet Assoc 104:222–225

    Article  PubMed  Google Scholar 

  27. Kuschnir MC, Mendonça GA (2007) Risk factors associated with arterial hypertension in adolescents. J Pediatr 83:335–342

    Article  Google Scholar 

  28. McGill HC Jr, McMahan CA, Herderick EE et al (2000) Origin of atherosclerosis in childhood and adolescence. Am J Clin Nutr 72:1307S–1315S

    PubMed  CAS  Google Scholar 

  29. Mendes-Lana A, Pena GG, Freitas SN et al (2007) Apolipoprotein E polymorphism in Brazilian dyslipidemic individuals: Ouro Preto study. Braz J Med Biol Res 40:49–56

    Article  PubMed  CAS  Google Scholar 

  30. Menezes AMB, Hallall PC, Hortal BL et al (2007) Size at birth and blood pressure in early adolescence: a prospective birth cohort study. Am J Epidemiol 165:611–616

    Article  PubMed  Google Scholar 

  31. Mikkilä V, Räsänen L, Raitakari OT et al (2005) Consistent dietary patterns identified from childhood to adulthood: the cardiovascular risk in young Finns study. Br J Nutr 93:923–931

    Article  PubMed  Google Scholar 

  32. Mion Júnior D, Junior OK, Gomes MAM et al. V Diretrizes Brasileiras de Hipertensão Arterial. São Paulo, Sociedade Brasileira de Hipertensão, Sociedade Brasileira de Cardiologia, Sociedade Brasileira de Nefrologia, 2006

  33. Moura EC, Castro CM, Mellin AS, Figueiredo DB (2000) Perfil lipídico em escolares de Campinas, SP. Brasil Rev Saude Publ 34:499–505

    CAS  Google Scholar 

  34. Mzayek F, Hassig S, Sherwin J et al (2007) The association of birth weight with developmental trends in blood pressure from childhood through mid-adulthood: the Bogalusa heart study. Am J Epidemiol 166:413–420

    Article  PubMed  CAS  Google Scholar 

  35. Needell J (1995) Identity, race, gender and modernity in the origins of Gilberto Freyre’s Ouevre. Am Hist Rev 100:51–77

    Article  Google Scholar 

  36. Nicklas TA, Demory-Luce D, Yang S et al (2004) Children’s food consumption patterns have changed over two decades (1973–1994): the Bogalusa heart study. J Am Diet Assoc 104:1127–1140

    Article  PubMed  Google Scholar 

  37. Reilly JJ, Armstrong J, Dorosty AR et al (2005) Early life risk factors for obesity in childhood: cohort study. Br Med J 330:1357–1364

    Article  Google Scholar 

  38. Ribeiro RQC, Lotufo PA, Lamounier JA et al (2006) Fatores adicionais de risco cardiovascular associados ao excesso de peso em crianças e adolescentes. O estudo do coração de Belo Horizonte. Arq Bras Cardiol 86:408–418

    Article  PubMed  Google Scholar 

  39. Rosamond W, Flegal K, Friday G et al (2007) Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115:e69–e171

    Article  PubMed  Google Scholar 

  40. Russell M, Simone GD, Resnick HE, Howard BV (2007) The metabolic syndrome in American Indians: the strong heart study. J Cardiometab Syndr 2:283–287

    Article  PubMed  Google Scholar 

  41. Sociedade Brasileira de Diabetes (2005) Atualização Brasileira sobre Diabetes. Diagraphic, Rio de Janeiro

    Google Scholar 

  42. Sorof J, Daniels S (2002) Obesity and hypertension in children. A problem of epidemic proportions. Hypertension 40:441–447

    Article  PubMed  CAS  Google Scholar 

  43. Stein A, Thompson A, Waters A (2005) Childhood growth and chronic disease: evidence from countries undergoing the nutrition transition. Matern Child Nutr 1:177–184

    Article  PubMed  Google Scholar 

  44. Talvia SA, Lagstrõm H, Rãsãnen M et al (2004) A randomized intervention since infancy to reduce intake of saturated fat. Arch Pediatr Adolesc Med 158:41–47

    Article  PubMed  Google Scholar 

  45. Taveras EM, Berkey CS, Rifas-Shiman SL et al (2005) Association of consumption of fried food away from home with body mass index and diet quality in older children and adolescents. Pediatrics 116:e518–e524

    Article  PubMed  Google Scholar 

  46. Trudeau F, Shephard RJ, Bouchard S, Laurencelle L (2003) BMI in the Trois-Rivieres study: child–adult and child–parent relationships. Am J Hum Biol 15:187–191

    Article  PubMed  Google Scholar 

  47. Victora CG, Sibbritt D, Horta BL et al (2007) Weight gain in childhood and body composition at 18 years of age in Brazilian males. Acta Pædiatr 96:296–300

    Article  PubMed  Google Scholar 

  48. Vongpatanasin W (2007) Cardiovascular morbidity and mortality in high-risk populations: epidemiology and opportunities for risk reduction. J Clin Hypertens 9:11–15

    Google Scholar 

  49. Williams SS (2007) Advances in genetic hypertension. Curr Opin Pediatr 19:192–198

    Article  PubMed  Google Scholar 

  50. Wolf-Maier K, Cooper RS, Banegas JR et al (2003) Hypertension prevalence and blood pressure levels in six European countries, Canada, and the United States. JAMA 289:2363–2369

    Article  PubMed  Google Scholar 

  51. World Health Organization (1995) WHO Expert Committee on Physical Status: the use and interpretation of anthropometry physical status. World Health Organization, Geneva [WHO Technical Report Series, vol. 854]

    Google Scholar 

Download references

Acknowledgements

The authors thank Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq (Grant no. 474965/04), Fundação de Amparo a Pesquisa do Estado de Minas Gerais—FAPEMIG (Grant CDS 770/05), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—CAPES and Prefeitura Municipal de Ouro Preto for financial support. WTC and GLLMC are recipients of a CNPq individual research grant of productivity.

Conflict of interest statement

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ana Paula C. Cândido.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cândido, A.P.C., Benedetto, R., Castro, A.P.P. et al. Cardiovascular risk factors in children and adolescents living in an urban area of Southeast of Brazil: Ouro Preto Study. Eur J Pediatr 168, 1373–1382 (2009). https://doi.org/10.1007/s00431-009-0940-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-009-0940-1

Keywords

Navigation