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Risk Factors and Implications of Childhood Obesity

  • Metabolism (M Dalamaga, Section Editor)
  • Published:
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Abstract

Purpose of Review

This review summarizes our current understanding of factors associated with childhood obesity, including latest prevalence rates, effectiveness of intervention strategies, and risk for concomitant disease later in life.

Recent Findings

Obesity has reached global dimensions, and prevalence of childhood obesity has increased eightfold since 1975. Interventions for obesity prevention have mainly focused on behavioral settings to date, i.e., interventions that have focused on behavioral changes of the individuum such as increasing daily physical exercise or optimizing diet. However, effects have been very limited worldwide and could not stop the increase of obesity prevalence so fare. Thus, community-based/environment-oriented measures are urgently needed, such as promotion of healthy food choices by taxing unhealthy foods, mandatory standards for meals in kindergarten and schools, increase of daily physical activity at kindergartens, and schools as well as ban on unhealthy food advertisement for children.

Summary

Restructuring obesity interventions towards community-based/environment-oriented measures to counteract an obesogenic environment is mandatory for sustainable success and to stop the obesity epidemy. There is need to move fast, as already moderate overweight before the start of puberty is associated with significantly increased risk for type 2 diabetes and cardiovascular disease in midlife.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388:1659–724.

    Article  Google Scholar 

  2. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–81.

    Article  Google Scholar 

  3. • GBD 2015 Obesity Collaborators. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017;377:13–26 The global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013 is presented. Obesity prevalence is increasing worldwide, and no national success stories have been reported in the past 33 years. Thus, urgent global action is needed.

    Article  Google Scholar 

  4. Olds T, Maher C, Zumin S, Péneau S, Lioret S, Castetbon K, et al. Evidence that the prevalence of childhood overweight is plateauing: data from nine countries. Int J Pediatr Obes. 2011;6:342–60.

    Article  Google Scholar 

  5. Blüher S, Meigen C, Gausche R, et al. Age-specific stabilization in obesity prevalence in German children: a cross-sectional study from 1999 to 2008. Int J Pediatr Obes. 2011;6:e199–206.

    Article  Google Scholar 

  6. Pervanidou P, Akalestos A, Bastaki D, Apostolakou F, Papassotiriou I, Chrousos G. Increased circulating High-Sensitivity Troponin T concentrations in children and adolescents with obesity and the metabolic syndrome: a marker for early cardiac damage? Metabolism. 2013;62:527–31.

    Article  CAS  Google Scholar 

  7. Wiegand S, Keller K, Röbl M, et al. Obese boys at increased risk for nonalcoholic liver disease: evaluation of 16,390 overweight or obese children and adolescents. Int J Obes. 2010;34:1468–74.

    Article  CAS  Google Scholar 

  8. Zimmet P, Alberti G, Kaufman F, Tajima N, Silink M, Arslanian S, et al. The metabolic syndrome in children and adolescents. Lancet. 2007;369:2059–61.

    Article  Google Scholar 

  9. Blüher S, Molz E, Wiegand S, Otto KP, Sergeyev E, Tuschy S, et al. Body Mass Index, waist circumference, and waist-to-height ratio as predictors of cardiometabolic risk in childhood obesity depending on pubertal development. J Clin Endocrinol Metab. 2013;98:3384–93.

    Article  Google Scholar 

  10. Mühlig Y, Wabitsch M, Moss A, Hebebrand J. Weight loss in children and adolescents. Dtsch Arztebl Int. 2014;111:818–24.

    PubMed  PubMed Central  Google Scholar 

  11. Oude Luttikhuis H, Baur L, Jansen H, et al. Interventions for treating obesity in children. Cochrane Database Syst Rev. 2009:CD001872. https://doi.org/10.1002/14651858.CD001872.pub2.

  12. •• Bjerregaard LF, Jensen BW, Ängquist L, Osler M, Sorensen T, Baker JL. Change in overweight from childhood to early adulthood and risk for type 2 diabetes. N Engl J Med. 2018;378(14):1302–12 The study has investigated 62,565 Danish men whose weights and heights had been measured at 7 and 13 years of age and in early adulthood (17 to 26 years of age). Childhood overweight at 7 years of age was associated with increased risk of adult type 2 diabetes only if it continued until puberty or later ages.

    Article  Google Scholar 

  13. Lange D, Wahrendorf M, Siegrist J, Plachta-Danielzik S, Landsberg B, Müller MJ. Associations between neighbourhood characteristics, body mass index and health-related behaviours of adolescents in the Kiel Obesity Prevention Study: a multilevel analysis. Eur J Clin Nutr. 2011;65:711–9.

    Article  CAS  Google Scholar 

  14. Ludwig J, Sanbonmatsu L, Gennetian L, Adam E, Duncan GJ, Katz LF, et al. Neighborhoods, obesity, and diabetes-a randomized social experiment. N Engl J Med. 2011;365:1509–19.

    Article  CAS  Google Scholar 

  15. Plachta-Danielzik S, Kehden B, Landsberg B, Schaffrath Rosario A, Kurth BM, Arnold C, et al. Attributable risks for childhood overweight: evidence for limited effectiveness of prevention. Pediatrics. 2012;130:e865–71.

    Article  Google Scholar 

  16. Weihrauch-Blüher S, Kromeyer-Hauschild K, Graf C, Widhalm K, Korsten-Reck U, Jödicke B, et al. Current guidelines for obesity prevention in childhood and adolescence. Obes Facts. 2018;11(3):263–76. https://doi.org/10.1159/000486512.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Gose M, Plachta-Danielzik S, Willié B, Johannsen M, Landsberg B, Müller M. Longitudinal influences of neighbourhood built and social environment on children’s weight status. Int J Environ Res Public Health. 2013;10:5083–96.

    Article  Google Scholar 

  18. • Hawkes C, Smith TG, Jewell J, et al. Smart food policies for obesity prevention. Lancet. 2015;385:2410–21 Four mechanisms through which food policies can affect diet are identified and presented. Comprehensive policy actions are needed that create an enabling environment for infants and children to learn healthy food preferences.

    Article  Google Scholar 

  19. Roberto CA, Swinburn B, Hawkes C, Huang TTK, Costa SA, Ashe M, et al. Patchy progress on obesity prevention: emerging examples, entrenched barriers, and new thinking. Lancet. 2015;385:2400–9.

    Article  Google Scholar 

  20. Maximova K, Kuhle S, Davidson Z, Fung C, Veugelers PJ. Cardiovascular risk factor profiles of normal and overweight children and adolescents: insights from the Canadian Health Measures Survey. Can J Cardiol. 2012;29(8):976–82.

    Article  Google Scholar 

  21. Berenson GS. Bogalusa heart study group. Health consequences of obesity. Pediatr Blood Cancer. 2012;58(1):117–21.

    Article  Google Scholar 

  22. Boyer BP, Nelson JA, Holub SC. Childhood body mass index trajectories predicting cardiovascular risk in adolescence. J Adolesc Health. 2015;56(6):599–605.

    Article  Google Scholar 

  23. Li S, Chen W, Srinivasan S, et al. Relation of childhood obesity/cardiometabolic phenotypes to adult cardiometabolic profile: the Bogalusa Heart Study. Am J Epidemiol. 2012;176(7):S142–9.

    Article  Google Scholar 

  24. Sénéchal M, Wicklow B, Wittmeier K, et al. Cardiorespiratory fitness and adiposity in metabolically healthy overweight and obese youth. Pediatrics. 2013;132(1):e85–92.

    Article  Google Scholar 

  25. Bouhours-Nouet N, Dufresne S, de Casson F, et al. High birth weight and early postnatal weight gain protect obese children and adolescents from truncal adiposity and insulin resistance: metabolically healthy but obese subjects? Diabetes Care. 2008;31(5):1031–6.

    Article  CAS  Google Scholar 

  26. Juonala M, Magnussen C, Berenson G, et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med. 2011;365(20):1876–85.

    Article  CAS  Google Scholar 

  27. Tirosh A, Shai I, Afek A, Dubnov-Raz G, Ayalon N, Gordon B, et al. Adolescent BMI trajectory and risk of diabetes versus coronary disease. N Engl J Med. 2011;364(14):1315–25.

    Article  CAS  Google Scholar 

  28. Hu Y, Bhupathiraju SN, de Koning L, Hu FB. Duration of obesity and overweight and risk of type 2 diabetes among US women. Obesity (Silver Spring). 2014;22:2267–73.

    Article  Google Scholar 

  29. •• Twig T, Yaniv G, Levine H, et al. Body Mass Index in 2.3 million adolescents and cardiovascular death in adulthood. N Engl J Med. 2016;374(25):2430–40 A BMI between the 50th to 74th percentiles (i.e., within the accepted normal range) during adolescence is already strongly associated with increased cardio-vascular and all-cause mortality during 40 years of follow-up. Thus, already mild overweight during adolescence may lead to significant morbidity and increased mortality in adulthood .

    Article  Google Scholar 

  30. Baker JL, Olsen LW, Sorensen TIA. Childhood body-mass index and the risk of coronary heart disease in adulthood. N Engl J Med. 2007;357:2329–37.

    Article  CAS  Google Scholar 

  31. NCD-Risk-Factor-Collaboration. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 2017. https://doi.org/10.1016/S0140-6736(17)32129-3.

    Article  Google Scholar 

  32. Waters E, de Silva-Sanigorski A, Hall B, et al. Interventions for preventing obesity in children. Cochrane Database Syst Rev. 2011:CD001871. https://doi.org/10.1002/14651858.

  33. Reinehr T. Long-term effects of adolescent obesity: time to act. Nat Rev Endocrinol. 2018;14(3):183–8.

    Article  Google Scholar 

  34. •• Iguacel I, Michels N, Ahrens W, Bammann K, Eiben G, Fernández-Alvira JM, et al. Prospective associations between socioeconomically disadvantaged groups and metabolic syndrome risk in European children. Results from the IDEFICS study. Int J Cardiol. 2018. https://doi.org/10.1016/j.ijcard.2018.07.053 Children from socioeconomically disadvantaged families are at high metabolic risk independently of diet, physical activity, sedentary behaviors, and well-being. As obesity interventions have failed to target these groups to date, future interventions should be developed to tackle health disparities.

    Article  Google Scholar 

  35. Weihrauch-Blüher S, Richter M, Staege MS. Body weight regulation, socioeconomic status and epigenetic alterations. Metabolism. 2018;85:109–15.

    Article  Google Scholar 

  36. Needham BL, Fernandez JR, Lin J. Socioeconomic status and cell aging in children. Soc Sci Med. 2012;74:1948–51.

    Article  Google Scholar 

  37. Swinburn BA, Sacks G, Hall KD, McPherson K, Finegood DT, Moodie ML, et al. The global obesity pandemic: shaped by global drivers and local environments. Lancet. 2011;378:804–14.

    Article  Google Scholar 

  38. Cespedes Feliciano EM, Quante M, Rifas-Shiman SL, Redline S, Oken E, Taveras EM. Objective sleep characteristics and cardiometabolic health in young adolescents. Pediatrics. 2018;142(1). https://doi.org/10.1542/peds.2017-4085.

    Article  Google Scholar 

  39. LeBourgeois MK, Hale L, Chang AM, Akacem LD, Montgomery-Downs HE, Buxton OM. Digital media and sleep in childhood and adolescence. Pediatrics. 2017;140(Suppl 2):S92–6.

    Article  Google Scholar 

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Correspondence to Susann Weihrauch-Blüher.

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Susann Weihrauch-Blüher and Susanna Wiegand declare they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Metabolism

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Weihrauch-Blüher, S., Wiegand, S. Risk Factors and Implications of Childhood Obesity. Curr Obes Rep 7, 254–259 (2018). https://doi.org/10.1007/s13679-018-0320-0

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  • DOI: https://doi.org/10.1007/s13679-018-0320-0

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