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Future perspectives and research initiatives in fast-track surgery

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Abstract

Background and aims

Major surgery is still followed by a risk of morbidity, a need for hospitalisation and convalescence. Fast-track surgery has been introduced as a coordinated effort to combine unimodal evidence-based principles of care into a multi-modal effort to enhance recovery. The aim of this article was to update recent data on fast-track abdominal surgery and outline future strategies for research.

Results

The data from fast-track colonic resection support the validity of the concept because pain, ileus, cardiopulmonary function and muscle function were all improved, compared with traditional treatment and with reduced post-operative fatigue and convalescence. Although less data is available, similar positive results may be achieved in other types of major surgery. Current research initiatives include improved multi-modal non-opioid analgesia, rational principles for perioperative fluid management, pharmacological reduction of surgical stress responses and the role of laparoscopic procedures within the fast-track concept.

Conclusions

Fast-track surgery has evolved as a valid concept to improve post-operative outcome. Further progress may be expected based upon intensified research within perioperative pathophysiology and a multi-disciplinary collaboration between surgeons, anaesthesiologists and surgical nurses.

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Correspondence to Henrik Kehlet.

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Kehlet, H. Future perspectives and research initiatives in fast-track surgery. Langenbecks Arch Surg 391, 495–498 (2006). https://doi.org/10.1007/s00423-006-0087-8

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  • DOI: https://doi.org/10.1007/s00423-006-0087-8

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