Neural and morphological changes in response to a 20-day intense eccentric training protocol

Abstract

The purpose of this study was to examine the time course of adaptation through 20 days of eccentric training and 5 days of detraining. A total of 22 untrained subjects trained one arm every 2nd day for 20 days. Subjects performed maximal isokinetic eccentric biceps brachii training at 90°/s (six sets of eight reps). Muscle thickness (reported in cm) via ultrasound, strength (reported in Nm) and muscle activation (electromyography) were measured before, during, and after training (nine time points). Strength in the trained arm decreased after 8 days of training (65.6 ± 4.1 to 57.5 ± 3.5; p < 0.05) and remained decreased throughout the study. Agonist muscle activation amplitude of the trained arm increased after 14 days of training (p < 0.05) and remained elevated throughout the study. Antagonist muscle activation decreased after 20 days of training (p < 0.05). Muscle thickness increased after 8 days of training (3.66 ± 0.11 to 3.90 ± 0.12; p < 0.05) and remained above baseline until the end of training (3.97 ± 0.12). After 5 days of detraining, muscle thickness decreased (3.97 ± 0.12 vs. 3.85 ± 0.11; p < 0.05), but remained higher than baseline (p < 0.05). Muscle thickness did not change significantly in the untrained arm at any time point. In conclusion, the early increase in biceps brachii muscle thickness coupled with a significant decrease in strength is an indicator of muscle damage leading to swelling and impaired muscle function. The persistent decrease in strength, despite an increase in muscle activation, suggests that the recovery interval was inadequate to allow complete repair of muscle damage. Intense eccentric training performed every 2nd day leads to a prolonged impairment of muscle strength in previously untrained individuals.