Abstract
Skeletal muscles fatigue after exercise, and reductions in maximal force appear. A difference in training status between the legs was introduced by unilateral immobilization of the calf muscles for 2 weeks in young men, who were randomly assigned to two groups, either a RUN group (n = 8) that was exposed to prolonged exercise (1-h running: individual pace) or a REST group (n = 12) that did no exercise after immobilization. Cross-sectional area (CSA) of the triceps-surae muscles was calculated by magnetic resonance imaging (MRI), and maximal voluntary contraction (MVC) force of the plantar flexors was measured before and after immobilization and after the running protocol. The CSA of triceps-surae muscles decreased significantly with a 7% reduction in both groups. A significant drop in the MVC of the triceps-surae muscle (10%; P < 0.05) was observed in response to immobilization. When subjected to running exercise immediately after immobilization, the muscle strength of the triceps-surae muscles dropped even further, but just in the immobilized leg (41%; P < 0.05). The present study highlights the importance of determining the muscle endurance when evaluating the effect of immobilization on muscle parameters.
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Alfredson H, Pietila T, Ohberg L, Lorentzon R (1998) Achilles tendinosis and calf muscle strength. The effect of short-term immobilization after surgical treatment. Am J Sports Med 26:166–171
Allen DG, Lamb GD, Westerblad H (2008) Skeletal muscle fatigue: cellular mechanisms. Physiol Rev 88:287–332. doi:10.1152/physrev.00015.2007
Alway SE, MacDougall JD, Sale DG, Sutton JR, McComas AJ (1988) Functional and structural adaptations in skeletal muscle of trained athletes. J Appl Physiol 64:1114–1120
Appell HJ (1990) Muscular atrophy following immobilisation. A review. Sports Med 10:42–58. doi:10.2165/00007256-199010010-00005
Berg HE, Tesch PA (1996) Changes in muscle function in response to 10 days of lower limb unloading in humans. Acta Physiol Scand 157:63–70. doi:10.1046/j.1365-201X.1996.476217000.x
Bigland-Ritchie B, Furbush F, Woods JJ (1986) Fatigue of intermittent submaximal voluntary contractions: central and peripheral factors. J Appl Physiol 61:421–429
Brown AB, McCartney N, Sale DG (1990) Positive adaptations to weight-lifting training in the elderly. J Appl Physiol 69:1725–1733
Christensen B, Dyrberg E, Aagaard P, Enehjelm S, Krogsgaard M, Kjaer M, Langberg H (2008) Effects of long-term immobilization and recovery on human triceps surae and collagen turnover in the Achilles tendon in patients with healing ankle fracture. J Appl Physiol 105:420–426. doi:10.1152/japplphysiol.00201.2008
Clark BC, Manini TM, Bolanowski SJ, Ploutz-Snyder LL (2006) Adaptations in human neuromuscular function following prolonged unweighting. II. Neurological properties and motor imagery efficacy. J Appl Physiol 101:264–272. doi:10.1152/japplphysiol.01404.2005
Clement DB, Taunton JE, Smart GW (1984) Achilles tendinitis and peritendinitis: etiology and treatment. Am J Sports Med 12:179–184. doi:10.1177/036354658401200301
Corbeil P, Blouin JS, Begin F, Nougier V, Teasdale N (2003) Perturbation of the postural control system induced by muscular fatigue. Gait Posture 18:92–100. doi:10.1016/S0966-6362(02)00198-4
Couppe C, Kongsgaard M, Aagaard P, Hansen P, Bojsen-Moller J, Kjaer M, Magnusson SP (2008) Habitual loading results in tendon hypertrophy and increased stiffness of the human patellar tendon. J Appl Physiol 105:805–810. doi:10.1152/japplphysiol.90361.2008
Cureton KJ, Collins MA, Hill DW, McElhannon FM Jr (1988) Muscle hypertrophy in men and women. Med Sci Sports Exerc 20:338–344. doi:10.1249/00005768-198808000-00003
Gandevia SC (2001) Spinal and supraspinal factors in human muscle fatigue. Physiol Rev 81:1725–1789
Hawkins RD, Hulse MA, Wilkinson C, Hodson A, Gibson M (2001) The association football medical research programme: an audit of injuries in professional football. Br J Sports Med 35:43–47. doi:10.1136/bjsm.35.1.43
Kannus P (1997) Etiology and pathophysiology of chronic tendon disorders in sports. Scand J Med Sci Sports 7:78–85
Karladani AH, Svantesson U, Granhed H, Styf J (2001) Postural control and torque of the knee joint after healed tibial shaft fracture. Injury 32:57–60. doi:10.1016/S0020-1383(00)00112-1
Lundbye-Jensen J, Nielsen JB (2008) Immobilization induces changes in presynaptic control of group Ia afferents in healthy humans. J Physiol 586:4121–4135. doi:10.1113/jphysiol.2008.156547
Maaløe L, Poulsen I (2003) Inaktivitet, immobilitet og sygepleje (inactivity, immobility and nursing), 2nd edn. Munksgaard, Denmark, pp 28–46
Maclaren DP, Gibson H, Parry-Billings M, Edwards RH (1989) A review of metabolic and physiological factors in fatigue. Exerc Sport Sci Rev 17:29–66
Magnusson SP, Beyer N, Abrahamsen H, Aagaard P, Neergaard K, Kjaer M (2003) Increased cross-sectional area and reduced tensile stress of the Achilles tendon in elderly compared with young women. J Gerontol A Biol Sci Med Sci 58:123–127
Mayhew JL, Piper FC, Ware JS (1993) Anthropometric correlates with strength performance among resistance trained athletes. J Sports Med Phys Fitness 33:159–165
Mulder ER, Kuebler WM, Gerrits KH, Rittweger J, Felsenberg D, Stegeman DF, de Haan A (2007) Knee extensor fatigability after bedrest for 8 weeks with and without countermeasure. Muscle Nerve 36:798–806. doi:10.1002/mus.20870
Narici M, Kayser B, Barattini P, Cerretelli P (2003) Effects of 17-day spaceflight on electrically evoked torque and cross-sectional area of the human triceps surae. Eur J Appl Physiol 90:275–282. doi:10.1007/s00421-003-0955-7
Nybo L, Nielsen B (2001) Hyperthermia and central fatigue during prolonged exercise in humans. J Appl Physiol 91:1055–1060
Ohberg L, Lorentzon R, Alfredson H (2001) Good clinical results but persisting side-to-side differences in calf muscle strength after surgical treatment of chronic Achilles tendinosis: a 5-year follow-up. Scand J Med Sci Sports 11:207–212. doi:10.1034/j.1600-0838.2001.110403.x
Ostenberg A, Roos H (2000) Injury risk factors in female European football. A prospective study of 123 players during one season. Scand J Med Sci Sports 10:279–285. doi:10.1034/j.1600-0838.2000.010005279.x
Pathare NC, Stevens JE, Walter GA, Shah P, Jayaraman A, Tillman SM, Scarborough MT, Parker GC, Vandenborne K (2006) Deficit in human muscle strength with cast immobilization: contribution of inorganic phosphate. Eur J Appl Physiol 98:71–78. doi:10.1007/s00421-006-0244-3
Petersen K, Hansen CB, Aagaard P, Madsen K (2007) Muscle mechanical characteristics in fatigue and recovery from a marathon race in highly trained runners. Eur J Appl Physiol 101:385–396. doi:10.1007/s00421-007-0504-x
Ploutz-Snyder LL, Tesch PA, Hather BM, Dudley GA (1996) Vulnerability to dysfunction and muscle injury after unloading. Arch Phys Med Rehabil 77:773–777. doi:10.1016/S0003-9993(96)90255-5
Salavati M, Moghadam M, Ebrahimi I, Arab AM (2007) Changes in postural stability with fatigue of lower extremity frontal and sagittal plane movers. Gait Posture 26:214–218. doi:10.1016/j.gaitpost.2006.09.001
Saldanha A, Nordlund Ekblom MM, Thorstensson A (2008) Central fatigue affects plantar flexor strength after prolonged running. Scand J Med Sci Sports 18:383–388
Schepsis AA, Jones H, Haas AL (2002) Achilles tendon disorders in athletes. Am J Sports Med 30:287–305
Sharpe MH, Miles TS (1993) Position sense at the elbow after fatiguing contractions. Exp Brain Res 94:179–182. doi:10.1007/BF00230480
Stehno-Bittel L, Reddy GK, Gum S, Enwemeka CS (1998) Biochemistry and biomechanics of healing tendon. Part I. Effects of rigid plaster casts and functional casts. Med Sci Sports Exerc 30:788–793. doi:10.1097/00005768-199806000-00002
Stevens JE, Pathare NC, Tillman SM, Scarborough MT, Gibbs CP, Shah P, Jayaraman A, Walter GA, Vandenborne K (2006) Relative contributions of muscle activation and muscle size to plantarflexor torque during rehabilitation after immobilization. J Orthop Res 24:1729–1736. doi:10.1002/jor.20153
Taylor JL, Butler JE, Gandevia SC (2000) Changes in muscle afferents, motoneurons and motor drive during muscle fatigue. Eur J Appl Physiol 83:106–115. doi:10.1007/s004210000269
Thorlund JB, Michalsik LB, Madsen K, Aagaard P (2008) Acute fatigue-induced changes in muscle mechanical properties and neuromuscular activity in elite handball players following a handball match. Scand J Med Sci Sports 18:462–472
Urso ML, Clarkson PM, Price TB (2006) Immobilization effects in young and older adults. Eur J Appl Physiol 96:564–571. doi:10.1007/s00421-005-0109-1
Vandenborne K, Elliott MA, Walter GA, Abdus S, Okereke E, Shaffer M, Tahernia D, Esterhai JL (1998) Longitudinal study of skeletal muscle adaptations during immobilization and rehabilitation. Muscle Nerve 21:1006–1012. doi:10.1002/(SICI)1097-4598(199808)21:8<1006::AID-MUS4>3.0.CO;2-C
Veitch SW, Findlay SC, Hamer AJ, Blumsohn A, Eastell R, Ingle BM (2006) Changes in bone mass and bone turnover following tibial shaft fracture. Osteoporos Int 17:364–372. doi:10.1007/s00198-005-2025-y
Vollestad NK (1997) Measurement of human muscle fatigue. J Neurosci Methods 74:219–227. doi:10.1016/S0165-0270(97)02251-6
Westerblad H, Allen DG (2002) Recent advances in the understanding of skeletal muscle fatigue. Curr Opin Rheumatol 14:648–652. doi:10.1097/00002281-200211000-00003
White MJ, Davies CT, Brooksby P (1984) The effects of short-term voluntary immobilization on the contractile properties of the human triceps surae. Q J Exp Physiol 69:685–691
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We thank Peter Butty for his great support by MRI scanning all subjects and Burt Farber for his generous contribution in correcting the language and the grammar of the paper.
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Pingel, J., Moerch, L., Kjaer, M. et al. The influence of training status on the drop in muscle strength after acute exercise. Eur J Appl Physiol 106, 605–611 (2009). https://doi.org/10.1007/s00421-009-1055-0
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DOI: https://doi.org/10.1007/s00421-009-1055-0