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Pain related potentials by electrical stimulation of skin for detection of small-fiber neuropathy in HIV

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Abstract

We compared the sensitivity of pain related evoked potentials (PREP), a novel electrophysiological technique, with standard nerve conduction (SNC) testing in the diagnosis of small fiber neuropathy in 47 patients with HIV infection and 31 age matched controls. SNC testing revealed a neuropathy in only 31%, whereas PREP was abnormal in 74% of symptomatic patients. This result hints that PREP is more sensitive in the detection of HIV-associated small fiber neuropathy than standard neurography.

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Authors and Affiliations

  1. Dept. of Neurology, University of Essen, Hufelandstr. 55, 45122, Essen, Germany

    Zaza Katsarava MD, Özgüt Yaldizli MD, Christina Voulkoudis MD, Hans-Christoph Diener MD & Matthias Maschke MD

  2. Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK

    Helger Kaube MD

Authors
  1. Zaza Katsarava MD
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  2. Özgüt Yaldizli MD
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  3. Christina Voulkoudis MD
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  4. Hans-Christoph Diener MD
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  5. Helger Kaube MD
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  6. Matthias Maschke MD
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Corresponding author

Correspondence to Zaza Katsarava MD.

Additional information

Received in revised form: 28 March 2006

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Katsarava, Z., Yaldizli, Ö., Voulkoudis, C. et al. Pain related potentials by electrical stimulation of skin for detection of small-fiber neuropathy in HIV. J Neurol 253, 1581–1584 (2006). https://doi.org/10.1007/s00415-006-0262-4

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  • DOI: https://doi.org/10.1007/s00415-006-0262-4

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