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The pedunculopontine tegmental nucleus and experimental parkinsonism

A review

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Abstract

In this article, I review a series of my experiments on the role of the pedunculopontine tegmental nucleus (Ppn) in voluntary movements. I sought to elucidate the functional role of the Ppn in the control of voluntary movements using macaque monkeys. I propose a functional model of basal ganglia circuitry in which I emphasize the role of the Ppn and discuss the underlying mechanisms of parkinsonism.

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  1. Neuroscience and Neurosurgery, Chuo Gunma Neurosurgery Hospital, 64-1,Nakao-machi, Takasaki, Gunma, 370-0001, Japan

    Masaru Matsumura

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  1. Masaru Matsumura
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Correspondence to Masaru Matsumura.

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Matsumura, M. The pedunculopontine tegmental nucleus and experimental parkinsonism. J Neurol 252 (Suppl 4), iv5–iv12 (2005). https://doi.org/10.1007/s00415-005-4003-x

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