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Von Mises stress peak (VMSP) and laryngomalacia severity score (LSS) are extremely useful in the selection of treatment for laryngomalacia

  • Laryngology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objective

To analyze the judgment efficiency of a computer stress model and severity score in severity evaluation and treatment plan selection of laryngomalacia patients.

Methods

Twenty-two children (12 cases in the operation group and 10 cases in the follow-up group) with moderate to severe laryngomalacia were assessed by laryngomalacia severity score (LSS) which included visual analogue scale (VAS) and clinical score. A computer stress model of the laryngeal cavity was constructed for all children, with the von Mises stress peak (VMSP) of the model used as another quantitative evaluation method. The ROC curves of two quantitative evaluation methods, the LSS and the VMSP, were analyzed respectively, according to the clinical guideline which is regarded as the gold standard for judging whether surgery is needed. The diagnostic efficiency indexes such as sensitivity, specificity, and accuracy were calculated. The area under ROC curves (AUC) of the two methods were compared by a DeLong model. Spearman correlation analysis and Kappa test were used to test the correlation and consistency of the two quantitative evaluation methods. The independent sample t test was used to compare the difference of LSS and VMSP between operation group and follow-up group.

Results

The sensitivity, specificity, and accuracy of LSS in judging whether laryngomalacia was operated or not were 83.33%, 80.00% and 81.82%, respectively, and the area under ROC curve (AUC) was 0.825 (p < 0.05). The sensitivity, specificity, and accuracy of the computer stress model for laryngomalacia were 58.33%, 90.00% and 72.73%, respectively, and the AUC was 0.796 (p < 0.05). The spearman correlation coefficient between LSS and VMSP was 0.833, p < 0.001, which is statistically significant. LSS (t = 3.251, p = 0.004) and VMSP (t = 2.435, p = 0.024) of the two groups were statistically different.

Conclusion

VMSP and LSS have high diagnostic efficacy in the quantitative evaluation of the severity of laryngomalacia and the selection of treatment plan. The consistency of the two quantitative evaluation methods is good, which has practical value for the evaluation of the severity of laryngomalacia and has guiding significance for surgery.

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Data availability

All data are available from the corresponding author upon reasonable request.

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Funding

This work was supported by the Foundation for Cross Biomedical Engineering of Shanghai Jiao Tong University (no. YG2019QNB02), the Youth Program of Shanghai Municipal Health Bureau (no. 20194Y0165), and the Clinical Research Project of Shanghai Shenkang Hospital Development Center (no. 20873999).

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Author notes

  1. Jiali Chen and Hongming Xu are the first authors and they contributed equally to this work.

Authors and Affiliations

  1. Department of Otorhinolaryngology Head and Neck Surgery, Children’s Hospital of Shanghai, Shanghai Jiao Tong University, 355th Luding Road, Shanghai, 200062, People’s Republic of China

    Jiali Chen, Hongming Xu & Xiaoyan Li

Authors
  1. Jiali Chen
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  2. Hongming Xu
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  3. Xiaoyan Li
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Corresponding author

Correspondence to Xiaoyan Li.

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This research did not increase the patients’ risk or economic burden, the patients’ rights were fully protected, and the project design was conducted in line with scientific and ethical principles. The institutional review board approved this project.

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Chen, J., Xu, H. & Li, X. Von Mises stress peak (VMSP) and laryngomalacia severity score (LSS) are extremely useful in the selection of treatment for laryngomalacia. Eur Arch Otorhinolaryngol 280, 3287–3293 (2023). https://doi.org/10.1007/s00405-023-07866-5

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