Abstract
A retrospective analysis of 31 lesions undergoing endoscopic surgery between 2006 and 2012 was undertaken. The data of patients’ demographics, clinical features, operative parameters, follow-up period, and treatment outcomes were collected. A total of 31 patients were reviewed and consisted of 19 females and 12 males. The median age was 23 years (range 6–55). The surgical strategy included the exclusive endoscopic approach in 26 cases, endoscopic approach with external approach in 5 cases. Twenty-two cases were achieved completely resection and nine cases were subtotally resected. During the follow-up period (median: 25 months, range 4–80 months), 4 cases developed recurrences and there was no evidence of recurrence in the additional 27 cases included 8 cases living with no progressively growing residual tumor and 19 cases living without diseases. Our experience indicates that the endoscopic approach to manage ossifying fibroma of the nose and paranasal sinuses is safe and effective. However, more cases and a longer period of follow-up are required to define its long-term therapeutic effect.
Similar content being viewed by others
References
Papadaki ME, Troulis MJ, Kaban LB (2005) Advances in diagnosis and management of fibro-osseous lesions. Oral Maxillofac Surg Clin N Am 17(4):415–434
Efune G et al (2012) Paranasal sinus and skull base fibro-osseous lesions: when is biopsy indicated for diagnosis? Int Forum Allergy Rhinol 2(2):160–165
Eversole LR, Leider AS, Nelson K (1985) Ossifying fibroma—a clinicopathologic study of 64 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 60(5):505–511
Choi YC, Jeon EJ, Park YS (2000) Ossifying fibroma arising in the right ethmoid sinus and nasal cavity. Int J Pediatr Otorhinolaryngol 54(2–3):159–162
Brannon RB, Fowler CB (2001) Benign fibro-osseous lesions: a review of current concepts. Adv Anat Pathol 8(3):126–143
Donnellan KA, Carron JD (2010) Endoscopic resection of an aggressive juvenile ossifying fibroma. Laryngoscope 120(Suppl 4):S223
Post G, Kountakis SE (2005) Endoscopic resection of large sinonasal ossifying fibroma. Am J Otolaryngol 26(1):54–56
Cansiz H et al (2004) Endoscope assisted removal of cementoossifying fibroma in the paranasal sinuses in a five-year-old girl. Int J Pediatr Otorhinolaryngol 68(4):489–493
Blitzer A, Post KD, Conley J (1989) Craniofacial resection of ossifying fibromas and osteomas of the sinuses. Arch Otolaryngol Head Neck Surg 115(9):1112–1115
Marvel JB, Marsh MA, Catlin FI (1991) Ossifying fibroma of the mid-face and paranasal sinuses: diagnostic and therapeutic considerations. Otolaryngol Head Neck Surg 104(6):803–808
Manes RP et al (2013) Ossifying fibroma of the nose and paranasal sinuses. Int Forum Allergy Rhinol 3(2):161–168
Sciubba JJ, Younai F (1989) Ossifying fibroma of the mandible and maxilla: review of 18 cases. J Oral Pathol Med 18(6):315–321
Johnson LC et al (1991) Juvenile active ossifying fibroma. Its nature, dynamics and origin. Acta Otolaryngol Suppl 488:1–40
Fu YS, Perzin KH (1974) Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. II. Osseous and fibro-osseous lesions, including osteoma, fibrous dysplasia, ossifying fibroma, osteoblastoma, giant cell tumor, and osteosarcoma. Cancer 33(5):1289–1305
Cox VS et al (1996) Ethmoidal cemento-ossifying fibroma: the transglabellar/subcranial approach. Otolaryngol Head Neck Surg 114(2):335–338
Chong VF, Tan LH (1997) Maxillary sinus ossifying fibroma. Am J Otolaryngol 18(6):419–424
Gezici AR, Ergun R (2008) Giant ossifying fibroma complicated by mucocele of sphenoid sinus—case report. Neurol Neurochir Pol 42(5):467–469
Bhat KV, Naseeruddin K (2002) Sublabial approach to sinonasal juvenile ossifying fibroma. Int J Pediatr Otorhinolaryngol 64(3):239–242
Cheng C et al (2002) Cemento-ossifying fibroma of maxillary and sphenoid sinuses: case report and literature review. Acta Otolaryngol Suppl 547:118–122
Hakeem AH, Hakeem IH (2013) Juvenile ossifying fibroma of paranasal sinuses-do we need to be radical in surgery? J Craniofac Surg 24(3):e257–e258
Wenig BM et al (1995) Aggressive psammomatoid ossifying fibromas of the sinonasal region: a clinicopathologic study of a distinct group of fibro-osseous lesions. Cancer 76(7):1155–1165
Mehta D et al (2006) Paediatric fibro-osseous lesions of the nose and paranasal sinuses. Int J Pediatr Otorhinolaryngol 70(2):193–199
Noudel R et al (2009) Transcranial resection of a large sinonasal juvenile psammomatoid ossifying fibroma. Childs Nerv Syst 25(9):1115–1120
Ledderose GJ et al (2011) Paranasal ossifying fibroma: endoscopic resection or wait and scan? Eur Arch Otorhinolaryngol 268(7):999–1004
Wong WK et al (2011) Role of intraoperative CT-updates during image-guided endoscopic sinus surgery for sinonasal fibro-osseous lesions. Auris Nasus Larynx 38(5):628–631
Ma J et al (2010) Resection of the ossifying fibroma of paranasal sinuses and anterior skull base with nasal endoscope under the guidance of image navigation. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 24(20):918–920, 927
Urs AB et al (2013) Clinicopathologic and radiologic correlation of ossifying fibroma and juvenile ossifying fibroma-an institutional study of 22 cases. Ann Diagn Pathol 17(2):198–203
Vaidya AM et al (1998) Juvenile aggressive ossifying fibroma presenting as an ethmoid sinus mucocele. Otolaryngol Head Neck Surg 119(6):665–668
Acknowledgments
The authors would like to thank van Maanen JP for his valuable contributions to the revision of the manuscript. This project was supported by the National Nature Science Foundation of China (No. 81070770) and Shanghai Municipal Hospitals’ Rising and Leading Technology Program (No. SHDC12013121).
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Additional information
H. Wang and X. Sun contributed equally to this article.
Rights and permissions
About this article
Cite this article
Wang, H., Sun, X., Liu, Q. et al. Endoscopic resection of sinonasal ossifying fibroma: 31 cases report at an institution. Eur Arch Otorhinolaryngol 271, 2975–2982 (2014). https://doi.org/10.1007/s00405-014-2972-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00405-014-2972-z