Abstract
The prognosis of cancer patients is highly dependent on the time of diagnosis. Early, stage 1 disease is often curable whereas late stage diseases are usually beyond curable treatments. Therefore, new diagnostic tools for malignancies of the upper aerodigestive tract are developed all the time and narrow band imaging (NBI) is one of these new options for early diagnostics. In this paper, we describe the implementation of NBI technique in our institution. During the first 6 weeks we used NBI to examine 73 patients with different types of pharyngeal or laryngeal problems. Most of the patients (77%) were on follow-up visits after earlier malignant disease. In our series we had 11 NBI-positive patients and the histological diagnosis was carcinoma or dysplasia among 10 of these. Among the NBI negative patients we found four carcinomas. It is notable that NBI affected the decision of a biopsy procedure in three patients, with final diagnosis of dysplasia or carcinoma. In conclusion, we find NBI useful in the diagnostics of malignancies of the upper aerodigestive tract. This is a useful tool in improving the accuracy of the diagnostics. However, it still takes an experienced clinician and a learning curve can be expected.
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References
Curado MP, Hashibe M (2009) Recent changes in the epidemiology of head and neck cancer. Curr Opin Oncol 21:194–200
D’Souza G, Kreimer AR, Viscidi R et al (2007) Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 356:1944–1956
Jensen AR, Nellemann HM, Overgaard J (2007) Tumor progression in waiting time for radiotherapy in head and neck cancer. Radiother Oncol 84:5–10
Hujala K, Sipila J, Grenman R (2005) Panendoscopy and synchronous second primary tumors in head and neck cancer patients. Eur Arch Otorhinolaryngol 262:17–20
Krueger H, McLean D, Williams D (2008) Cancers of the head and neck. Prog Exp Tumor Res 40:62–84
Farhadieh RD, Salardini A, Yang JL, Russell P, Smee R (2009) Diagnosis of second head and neck tumors in primary laryngeal SCC is an indicator of overall survival and not associated with poorer overall survival: a single centre study in 987 patients. J Surg Oncol 101:72–77
Muto M, Katada C, Sano Y, Yoshida S (2005) Narrow band imaging: a new diagnostic approach to visualize angiogenesis in superficial neoplasia. Clin Gastroenterol Hepatol 3:S16–S20
Piazza C, Dessouky O, Peretti G, Cocco D, De Benedetto L, Nicolai P (2008) Narrow-band imaging: a new tool for evaluation of head and neck squamous cell carcinomas. Review of the literature. Acta Otorhinolaryngol Ital 28:49–54
Piazza C, Cocco D, De Benedetto L, Del Bon F, Nicolai P, Peretti G (2010) Narrow band imaging and high definition television in the assessment of laryngeal cancer: a prospective study on 279 patients. Eur Arch Otorhinolaryngol 267:409–414
Ugumori T, Muto M, Hayashi R, Hayashi T, Kishimoto S (2009) Prospective study of early detection of pharyngeal superficial carcinoma with the narrowband imaging laryngoscope. Head Neck 31:189–194
Watanabe A, Tsujie H, Taniguchi M, Hosokawa M, Fujita M, Sasaki S (2006) Laryngoscopic detection of pharyngeal carcinoma in situ with narrowband imaging. Laryngoscope 116:650–654
Arens C, Reussner D, Woenkhaus J, Leunig A, Betz CS, Glanz H (2007) Indirect fluorescence laryngoscopy in the diagnosis of precancerous and cancerous laryngeal lesions. Eur Arch Otorhinolaryngol 264:621–626
Boller D, Spieler P, Schoenegg R, et al. (2009) Lugol chromoendoscopy combined with brush cytology in patients at risk for esophageal squamous cell carcinoma. Surg Endosc [Epub ahead of print]
Muto M, Nakane M, Katada C et al (2004) Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites. Cancer 101:1375–1381
Cikojevic D, Gluncic I, Pesutic-Pisac V (2008) Comparison of contact endoscopy and frozen section histopathology in the intra-operative diagnosis of laryngeal pathology. J Laryngol Otol 122:836–839
Andrea M, Dias O, Santos A (1995) Contact endoscopy during microlaryngeal surgery: a new technique for endoscopic examination of the larynx. Ann Otol Rhinol Laryngol 104:333–339
Arens C, Glanz H, Dreyer T, Malzahn K (2003) Compact endoscopy of the larynx. Ann Otol Rhinol Laryngol 112:113–119
Piazza C, Cocco D, De Benedetto L, Bon FD, Nicolai P, Peretti G (2010) Role of narrow-band imaging and high-definition television in the surveillance of head and neck squamous cell cancer after chemo- and/or radiotherapy. Eur Arch Otorhinolaryngol [Epub ahead of print]
Lin YC, Watanabe A, Chen WC, Lee KF, Lee IL, Wang WH (2010) Narrowband imaging for early detection of malignant tumors and radiation effect after treatment of head and neck cancer. Arch Otolaryngol Head Neck Surg 136:234–239
Acknowledgments
This work has been supported with research grants from Finnish Medical Foundation, Foundation for Otorhinolaryngological Research in Finland and Kirsti and Tor Johanssons Heart and Cancer Foundation.
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Irjala, H., Matar, N., Remacle, M. et al. Pharyngo-laryngeal examination with the narrow band imaging technology: early experience. Eur Arch Otorhinolaryngol 268, 801–806 (2011). https://doi.org/10.1007/s00405-011-1516-z
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DOI: https://doi.org/10.1007/s00405-011-1516-z