Abstract
The biochemical analysis of nasal secretions has become essential in the study of nasal or sinus diseases and the monitoring of medical and surgical treatment. The nasal fluid greatly reflects the inflammatory activity within the nasal mucosa. This paper discusses techniques for nasal fluid collection described before and proposes a new approach for the collection and calculation of nasal secretions based on sinus packs. The method is non-invasive, well standardized and reproducible and therefore may serve as a valid tool for future investigations.
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Acknowledgements
This work was supported by grant no. 01104101 from the Ghent University Research Foundation and grant no. G.0143.01 from the Research Program of the Fund for Scientific Research-Flanders (Belgium) (FWO-Vlaanderen).
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Drs. Watelet and Gevaert contributed equally to this work.
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Watelet, JB., Gevaert, P., Holtappels, G. et al. Collection of nasal secretions for immunological analysis. Eur Arch Otorhinolaryngol 261, 242–246 (2004). https://doi.org/10.1007/s00405-003-0691-y
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DOI: https://doi.org/10.1007/s00405-003-0691-y