Skip to main content
Log in

Prepregnancy body mass index and adverse pregnancy outcomes

  • Original Article
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

The aim of this study was to evaluate the association between prepregnancy BMI, and adverse maternal and neonatal outcomes.

Method

In this retrospective cohort study 916 consecutive singleton gestations were included who gave birth between 1 January 2006 and 31 August 2006 at the Department of Obstetrics and Gynecology, University of Udine, Italy. Statistical analysis was performed using univaried logistic regression and measured by odds ratio.

Results

The obese patients had a statistically, significantly increased incidence of Caesarean section (OR = 2.17, p = 0.009). Women with overweight (OR = 2.43, p = 0.002) and obese weight (OR = 4.86, p < 0.0001) were at increased risk for preterm deliveries. The pre-eclampsia and the fetal macrosomia (≥4,000 g) were increased in obese women (OR = 5.68, p < 0.0001; OR = 2.58, p = 0.033, respectively).

Conclusion

Maternal prepregnancy obesity is significantly associated with increased risk of Caesarean section, preterm delivery, pre-eclampsia and macrosomia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Pagano R, La Vecchia C (1994) Overweight and obesity in Italy, 1990–91. Int J Obes Relat Metab Disord 18(10):665–669

    PubMed  CAS  Google Scholar 

  2. Cedergren MI (2004) Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol 103:219–224

    PubMed  Google Scholar 

  3. Rosenberg TJ, Garbers S, Chavkin W, Chiasson MA (2003) Prepregnancy weight and adverse perinatal outcomes in an ethnically diverse population. Obstet Gynecol 102:1022–1027

    Article  PubMed  Google Scholar 

  4. Cedergren MI, Kallén BAJ (2003) Maternal obesity and infant heart defects. Obes Res 11:1065–1071

    Article  PubMed  Google Scholar 

  5. Watkins ML, Rasmussen SA, Honein MA, Botto LD, Morre CA (2003) Maternal obesity and risk for birth defects. Pediatrics 11:1152–1158

    Google Scholar 

  6. Vahratian A, Siega-riz AM, Savitz DA, Zhang AJ (2005) Maternal pre-pregnancy overweight and obesity and the risk of caesarean delivery in nulliparous women. Ann Epidemiol 15:467–474

    Article  PubMed  Google Scholar 

  7. Young TK, Woodmansee B (2002) Factors that are associated with caesarean delivery in a large private practice: the importance of prepregnancy body mass index and weight gain. Am J Obstet Gynecol 187:312–320

    Article  PubMed  Google Scholar 

  8. World Health Organization (1997) Preventing and managing the global epidemic. Report of the World Health Organization on obesity. WHO, Geneva

    Google Scholar 

  9. Galtier-Dereure F, Boegner C, Bringer J (2000) Obesity and pregnancy: complications and cost. Am J Clin Nutr 71(suppl):1242S–1248S

    PubMed  CAS  Google Scholar 

  10. Atalah E, Castro R (2004) Maternal obesity and reproductive risk. Rev Med Chil 132(8):923–930

    PubMed  Google Scholar 

  11. Bianco AT, Smilen SW, Davis Y, Lopez S, Lapinski R, Lockwood CJ (1998) Pregnancy outcome and weight gain recommendations for the morbidly obese woman. Obstet Gynecol 91:97–102

    Article  PubMed  CAS  Google Scholar 

  12. Godfrey KM, Barker DJP (2000) Fetal nutrition and adult disease. Am J Clin Nutr 71(suppl):1344S–1352S

    PubMed  CAS  Google Scholar 

  13. Kaufman H, Jacques D, Coleman S, Ganzeier G (2001) Prepregnancy body mass index and pregnancy outcome. Wednesday Posters 97(4)

  14. Kumari AS (2001) Pregnancy outcome in women with morbid obesity. Int J Gynecol Obstet 73:101–107

    Article  CAS  Google Scholar 

  15. Ricart W, Lopez J, Mozas J, Pericot A, Sancho MA, Gonzalez N et al (2005) Body mass index has a greater impact on pregnancy outcomes than gestational hyperglycaemia. Diabetologia 48(9):1736–1742

    Article  PubMed  CAS  Google Scholar 

  16. Ray JG, Vermeulen MJ, Shapiro JL, Kenshole AB (2001) Maternal and neonatal outcomes in pregestational and gestational diabetes mellitus, and the influence of maternal obesity and weight gain: the DEPOSIT study. Diabet Endocr Pregnancy Outcome Study Tor 94(7):347–356

    CAS  Google Scholar 

  17. Usha Kiran TS, Hemmadi S, Bethel J, Evans J (2005) Outcome of pregnancy in a woman with an increased body mass index. BJOG 112(6):768–772

    Article  PubMed  CAS  Google Scholar 

  18. Jensen DM, Ovesen P, Beck-Nielsen H, Mølsted-Pedersen L, Sørensen B, Vinter C et al (2005) Gestational weight gain and pregnancy outcomes in 481 obese glucose-tolerant women. Diabetes Care 28:2118–2122

    Article  PubMed  Google Scholar 

  19. Lumme R, Rantakallio P, Hartikainen AL, Jarvelin MR (1995) Prepregnancy weight and its relation to pregnancy outcome. J Obstet Gynaecol 15:69–75

    Article  Google Scholar 

  20. Ronnenberg AG, Wang X, Xing H, Chen C, Chen D, Guang W et al (2003) Low preconception body mass index is associated with birth outcome in a prospective cohort of Chinese women. J Nutr 133:3449–3455

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Driul.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Driul, L., Cacciaguerra, G., Citossi, A. et al. Prepregnancy body mass index and adverse pregnancy outcomes. Arch Gynecol Obstet 278, 23–26 (2008). https://doi.org/10.1007/s00404-007-0524-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-007-0524-0

Keywords

Navigation