Skip to main content

Advertisement

SpringerLink
Log in

Diagnostic and therapeutic problems of giant cell tumor in the proximal femur

  • Orthopaedic Surgery
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Primaly giant cell tumor of bone (GCT) in the proximal femur is relatively rare, and can prove difficult to diagnose, and can require therapeutic methods. Subjects comprised 10 patients (8 males, 2 females). Mean patient age was 27.5 years, and mean follow-up was 89.9 months. Tumors in the present study were limited to H1 and H2 according to the International Society of Limb Salvage (ISOLS) system. All patients received surgical treatment only. Second surgery after preoperative open biopsy was performed for two patients, while the remaining eight patients received excisional biopsy to determine treatment methods using rapid intraoperative pathological examination of frozen sections. The mean functional score was 28.2 out of 30 (93.9%). Local recurrence was observed in two patients. The long-term follow-up reveals that one of the important problem is pre-operative diagnosis. Excisional biopsy is effective for surgery of GCT in the proximal femur.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Adler CP (1995) Solid aneurysmal bone cyst with pathological bone fracture. Skeletal Radiol 24:214–216

    Article  PubMed  CAS  Google Scholar 

  2. Aoki J, Tanikawa H, Ishii K et al (1996) MR findings indicative of hemosiderin in giant-cell tumor of bone: frequency, cause, and diagnostic significance. Am J Roentgenol 166:145–148

    CAS  Google Scholar 

  3. De Silva MVC, Reid R (2003) Chondroblastoma: varied histologic appearance, potential diagnostic pitfalls, and clinicopathologic features associated with local recurrence. Ann Diagn Pathol 7:205–213

    Article  PubMed  Google Scholar 

  4. Dowdy PA, Griffin AM, White LM et al (1998) Bone sarcoma diagnosed at the time of reconstructive hip surgery. Can J Surg 41:273–282

    PubMed  CAS  Google Scholar 

  5. Enneking WF, Dunham W, Gebhardt MC et al (1993) A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop 286:241–246

    PubMed  Google Scholar 

  6. Fanning CV, Sneige NS, Carrasco CH et al (1990) Fine needle aspiration cytology of chondroblastoma of bone. Cancer 65:1847–18633

    Article  PubMed  CAS  Google Scholar 

  7. Irwin RB, Sauchak JA, O’Brien MP (1998) Tumors of the proximal femur: case examples and literature review. Orthopedics 21:182–189

    PubMed  CAS  Google Scholar 

  8. Koh JS, Chung JH, Lee SY et al (2001) Chondroblastoma of the proximal femur with myxoid degeneration mistaken for chondromyxoid fibroma in a young adults. A case report. Acta Cytol 45:254–258

    PubMed  CAS  Google Scholar 

  9. Komiya S, Inoue A (1993) Cementation in the treatment of giant cell tumor of bone. Arch Orthop Trauma Surg 112:51–55

    Article  PubMed  CAS  Google Scholar 

  10. Kulkarni SS, Dogra AS, Bhosale PB (1996) Total hip arthroplasty for giant cell tuour. J Postgrad Med 42:82–84

    PubMed  CAS  Google Scholar 

  11. Kumta SM, Leung PC, Yip K et al (1998) Vascularized bone grafts in the treatment of juxta-articular giant-cell tumors of the bone. J Reconstr Microsurg 14:185–190

    Article  PubMed  CAS  Google Scholar 

  12. Leung PC, Chow YYN (1984) Reconstruction of proximal femoral defects with a vascular-pedicled graft. J Bone Joint Surg (Br) 66:32–37

    CAS  Google Scholar 

  13. Malawer MM, Dunham W (1991) Cryosurgery and acrylic cementation as surgical adjuncts in the treatment of aggressive (benign) bone tumors. Analysis of 25 patients below the age of 21. Clin Orthop 262:42–57

    PubMed  Google Scholar 

  14. Murphey MD, Nomikos GC, Flemming DJ et al (2001) From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic–pathologic correlation. Radiographics 21:1283–1309

    PubMed  CAS  Google Scholar 

  15. Oda Y, Miura H, Tsuneyoshi M et al (1998) Giant cell tumor of bone: oncological and functional results of long-term follow-up. Jpn J Clin Oncol 28:323–328

    Article  PubMed  CAS  Google Scholar 

  16. O’Donnell RJ, Springfield DS, Motwani HK et al (1994) Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. J Bone Joint Surg (Am) 76:1827–1833

    CAS  Google Scholar 

  17. Ogose A, Hotta T, Hatano H et al (2002) Histological examination of beta-tricalcium phosphate graft in human femur. J Biomed Mater Res 63:601–604

    Article  PubMed  CAS  Google Scholar 

  18. Schajowicz F (1981) Giant cell tumor (osteocrastoma). In: Shajowicz F (ed) Tumours and tumour like lesions of bone and joints. Springer, New York, 205 pp

    Google Scholar 

  19. Sim E, Lang S (1997) Joint salvaging surgery for an extensive giant cell tumor of the proximal femur complicated by a transcervical fracture. Arch Orthop Trauma Surg 116:431–434

    PubMed  CAS  Google Scholar 

  20. Temple HT, Kuklo TR, Lehman RA Jr et al (2000) Segmental limb reconstruction after tumor resection. Am J Orthop 29:524–529

    Article  PubMed  CAS  Google Scholar 

  21. Wai EK, Davis AM, Griffin A et al (2001) Pathologic fractures of the proximal femur secondary to benign bone tumors. Clin Orthop 393:279–286

    Article  PubMed  Google Scholar 

  22. Yip KMH, Leung PC, Kumta SM (1996) Giant cell tumor of bone. Clin Orthop 323:60–64

    Article  PubMed  Google Scholar 

  23. Zwart HJ, Taminiau AH, Schimmel JW et al (1994) Kottz modular femur and tibia replacement. 28 tumor cases followed for 3(1–8) years. Acta Orthop Scand 65:315–318

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Ehime University School of Medicine, Shitsukawa, Toon, 791-0295, Ehime, Japan

    Kenshi Sakayama, Teruki Kidani, Joji Miyawaki, Taketsugu Fujibuchi, Setsuya Kamei, Junichi Aizawa & Haruyasu Yamamoto

  2. Department of Radiology, Ehime University School of Medicine, Shitsukawa, Toon, 791-0295, Ehime, Japan

    Yoshifumi Sugawara

Authors
  1. Kenshi Sakayama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yoshifumi Sugawara
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Teruki Kidani
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Joji Miyawaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Taketsugu Fujibuchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Setsuya Kamei
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Junichi Aizawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Haruyasu Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kenshi Sakayama.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sakayama, K., Sugawara, Y., Kidani, T. et al. Diagnostic and therapeutic problems of giant cell tumor in the proximal femur. Arch Orthop Trauma Surg 127, 867–872 (2007). https://doi.org/10.1007/s00402-007-0419-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00402-007-0419-3

Keywords

Search

Navigation