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Cystic leukomalacia in the cerebellar folia of premature infants

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Abstract

Cystic necrosis in the cerebellar white matter was found in three premature infants. The necrosis was characteristically localized in the center of the white matter of the superficial cerebellar folia, sparing the overlying cortex. The patients were aged between 28 and 34 gestational weeks, and had a clinical history of severe systemic hypotension. Thus, cystic leukomalacia represents a characteristic brain lesion in premature infants which may be caused by cerebellar hypoperfusion.

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Authors and Affiliations

  1. Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, 187, Kodaira, Tokyo, Japan

    Akira Tsuru, Masashi Mizuguchi & Sachio Takashima

Authors
  1. Akira Tsuru
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  2. Masashi Mizuguchi
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  3. Sachio Takashima
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Tsuru, A., Mizuguchi, M. & Takashima, S. Cystic leukomalacia in the cerebellar folia of premature infants. Acta Neuropathol 90, 400–402 (1995). https://doi.org/10.1007/BF00315013

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  • DOI: https://doi.org/10.1007/BF00315013

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