References
Bielle F, Di Stefano AL, Meyronet D, Picca A, Villa C, Bernier M et al (2018) Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features. Brain Pathol 28:674–683. https://doi.org/10.1111/bpa.12563
Bitar M, Danish SF, Rosenblum MK (2018) A newly diagnosed case of polymorphous low-grade neuroepithelialtumor of the young. ClinNeuropathol 37:178–181. https://doi.org/10.5414/np301081
Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C et al (2018) DNA methylation-based classification of central nervous system tumours. Nature 555:469–474. https://doi.org/10.1038/nature26000
Cheng DT, Mitchell TN, Zehir A, Shah RH, Benayed R, Syed A, Chandramohan R et al (2015) Memorial sloankettering-integrated mutation profiling of actionable cancer targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. J MolDiagn 17:251–264. https://doi.org/10.1016/j.jmoldx.2014.12.006
Gupta VR, Giller C, Kolhe R, Forseen SE, Sharma S (2019) Polymorphous low-grade neuroepithelialtumor of the young: a case report with genomic findings. World Neurosurg 132:347–355. https://doi.org/10.1016/j.wneu.2019.08.221
Huse JT, Snuderl M, Jones DT, Brathwaite CD, Altman N, Lavi E et al (2017) Polymorphous low-grade neuroepithelialtumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway. ActaNeuropathol 133:417–429. https://doi.org/10.1007/s00401-016-1639-9
Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B et al (2016) Genetic alterations in uncommon low-grade neuroepithelialtumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. ActaNeuropathol 131:833–845. https://doi.org/10.1007/s00401-016-1539-z
Shen R, Seshan VE (2016) FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing. Nucleic Acids Res 44:e131. https://doi.org/10.1093/nar/gkw520
Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B et al (2013) Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 45:602–612. https://doi.org/10.1038/ng.2611
Zheng Z, Liebers M, Zhelyazkova B, Cao Y, Panditi D, Lynch KD et al (2014) Anchored multiplex PCR for targeted next-generation sequencing. Nat Med 20:1479–1484. https://doi.org/10.1038/nm.3729
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Bale, T.A., Sait, S.F., Benhamida, J. et al. Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY). Acta Neuropathol 141, 123–125 (2021). https://doi.org/10.1007/s00401-020-02245-4
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00401-020-02245-4